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Synairgen announces data from Home Cohort of SG016 Phase II trial of inhaled interferon beta in COVID-19 patients and encouraging combined data for whole SG016 trial


1
: Synairgen plc (LSE: SNG), the respiratory company developing inhaled interferon beta (IFN-beta) for the treatment of severe viral lung infections, today announces results from the Home Cohort of its SG016 Phase II trial of SNG001 in SARS-CoV-2 infected patients and data from the combined analysis of the Hospital and Home Cohorts.
SNG001 is a formulation containing IFN-beta for nebulisation, allowing it to be delivered directly into patients’ lungs. A number of studies have reported that the SARS-CoV-2 virus suppresses natural production of IFN-beta and prevents induction of anti-viral responses by infected cells. Furthermore, some people have deficiencies in antiviral IFN signalling that make them more vulnerable to spread of the virus from the nose into the lungs where it can cause severe breathing difficulties. These findings provide a rationale to deliver IFN-beta directly to the surface epithelial cells of the lungs, the primary site of virus infection in the lun ....

United Kingdom , Olivia Manser , Geoff Nash , Mary Conway , Nick Francis , Richard Marsden , John Ward , Tom Wilkinson , Donna Davies , Duncan Monteith , Jessica Hodgson , James Black , Kate Bannatyne , Ratko Djukanovic , Mary Jane Elliott , Freddie Barnfield , Numis Securities Limited Joint Broker , University Of Southampton , United Kingdom National Institute For Health Research , Drug Administration , Consilium Strategic Communications Financial Media , National Institute For Health Research , University Of Southampton Professors Sir Stephen Holgate , Urgent Public Health , Foundation Trust Southampton , University Hospital Southampton ,

Menopausal symptoms in breast cancer patients could be reduced through CBT delivered by nurses


Menopausal symptoms in breast cancer patients could be reduced through CBT delivered by nurses
Apr 27 2021
Menopausal symptoms - hot flushes and night sweats – experienced by women with breast cancer can be reduced through group cognitive behavioral therapy (CBT) delivered by breast care nurses, a new clinical trial reveals.
Up to 85% of women with breast cancer suffer from hot flushes and night sweats due to chemotherapy and hormone therapy treatments. These side effects are often more extreme and can last longer for women with breast cancer than for women who experience them due to natural menopause. Hormone replacement therapy (HRT) may be offered to relieve menopausal symptoms, but is not usually recommended for women with breast cancer because it may increase their risk of the disease returning, therefore safe and effective alternatives to reduce side effects and ensure quality of life are urgently needed. ....

United Kingdom , City Of , Simon Vincent , Natalie Richards , Myra Hunter , Deborah Fenlon , King Io , British Menopause Society , Psychology Neuroscience At King College London , University Of Southampton , Health Boards , Institute Of Psychiatry , Swansea University , Breast Cancer Now , Professor Deborah Fenlon , Southampton Clinical Trials Unit , College London , Breast Cancer , Cancer Now , Professor Fenlon , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , சிமோன் வின்சென்ட் , நடாலி ரிச்சர்ட்ஸ் , கிங் ஐயொ , பிரிட்டிஷ் மாதவிடாய் சமூகம் ,