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Study: Pain Regimen Treats Surgical Trauma Patients with Fewer Opioids

CHICAGO A recently released study shows that a multimodal pain regimen (MMPR) designed to minimize opioid exposure and relieve acute pain associated with traumatic injury kept patient self-reported pain scores low while also reducing the daily and total amount of opioid drugs given to trauma patients.
Results from the first study of its kind to evaluate an MMPR in a rigorous, randomized controlled trial were published online as an “article in press” by the
Journal of the American College of Surgeons in advance of print.
“Opioids should not be considered the pillar of treatment for acute pain after injury,” said lead study author John A. Harvin, MD, FACS, associate professor for the department of surgery, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth) and trauma surgeon at the Red Duke Trauma Institute at Memorial Hermann-Texas Medical Center. ....

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Modified pain management strategy reduces opioid exposure to trauma patients, study shows

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IMAGE: John Harvin, MD, led a team of physician-researchers to identify an opioid-minimizing pain management strategy for patients with acute trauma.
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Credit: Cody Duty/UTHealth
A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at The University of Texas Health Science Center at Houston (UTHealth.)
Results of the study, which was conducted at the Red Duke Trauma Institute at Memorial Hermann-Texas Medical Center, were published today in the
Journal of American College of Surgeons.
The research shows us that seriously injured people with acute pain can effectively be treated with an opioid-minimizing strategy, said John Harvin, MD, MS, associate professor in the Department of Surgery at McGovern Medical School at UTHealth and first and corresponding author of ....

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Multimodal pain regimen minimizes opioid exposure, relieves acute pain in trauma patients

Multimodal pain regimen minimizes opioid exposure, relieves acute pain in trauma patients
A multimodal pain regimen (MMPR) designed to minimize opioid exposure and relieve acute pain associated with traumatic injury kept patient self-reported pain scores low while also reducing the daily and total amount of opioid drugs given to trauma patients. Results from the first study of its kind to evaluate an MMPR in a rigorous, randomized controlled trial are published online as an article in press by the
Journal of the American College of Surgeons in advance of print.
Opioids should not be considered the pillar of treatment for acute pain after injury, said lead study author John A. Harvin, MD, FACS, an associate professor for the department of surgery, McGovern Medical School, The University of Texas Health Science Center at Houston (UTHealth) and trauma surgeon at the Red Duke Trauma Institute at Memorial Hermann-Texas Medical Center. ....

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First patient enrolled in Phase II clinical trial of stem cell therapy for traumatic injuries

First patient enrolled in Phase II clinical trial of stem cell therapy for traumatic injuries
The first patient has enrolled in a Phase II clinical trial evaluating a stem cell therapy for the potential early treatment of traumatic injuries and their subsequent complications at The University of Texas Health Science Center at Houston (UTHealth).
The MATRICS-1 (MultiStem
® Administration for Trauma Related Inflammation and Complications) study is being conducted at Memorial Hermann-Texas Medical Center.
According to the Centers for Disease Control (CDC), trauma is the leading cause of death for individuals under the age of 45 and the third leading cause of death in the U.S., accounting for approximately 180,000 fatalities each year. It is also a leading cause of serious disability, especially among young people and members of the military that suffer trauma. ....

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