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Toxoplasmosis: An important risk factor for acquiring SARS-CoV-2 infection and a severe course of Covid-19 disease


Background Latent toxoplasmosis, i.e. a lifelong infection with the protozoan parasite
Toxoplasma gondii, affects about a third of human population worldwide. In the past ten years, numerous studies had shown that infected subjects have a significantly higher incidence of mental and physical health problems and are more prone to exhibiting the adverse effects of various diseases.
Methods A cross-sectional internet study was performed on a population of 4,499
Toxoplasma-free and 786
Toxoplasma-infected subjects and looked for factors which positively or negatively affect the risk of SARS-CoV-2 infection and likelihood of a severe course of Covid-19.
Findings Logistic regression and partial Kendall correlation controlled for sex, age, and size of the place of residence showed that latent toxoplasmosis had the strongest effect on the risk of infection (OR = 1·50) before sport (OR = 1·30), and borreliosis (1·27). It also had the strongest effect on the risk o ....

Czech Republic , Slovak Republic , Fakulty Univerzity Karlovy , Czech Science Foundation , Charles University Research Centre , Charles University Komise , Disability Adjusted Life Year , Institutional Review Board , Charles University , Open Science Framework , Partial Kendall , Anna Pil , Research Centre , செக் குடியரசு , ஸ்லோவாக் குடியரசு , செக் அறிவியல் அடித்தளம் , சார்லஸ் பல்கலைக்கழகம் ஆராய்ச்சி மையம் , நிறுவன விமர்சனம் பலகை , சார்லஸ் பல்கலைக்கழகம் , திறந்த அறிவியல் கட்டமைப்பு , ஆராய்ச்சி மையம் ,