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Data Demonstrate Efficacy of Silmitasertib Plus Gemcitabine and Cisplatin Combination Treatment for Cholangiocarcinoma

Data Demonstrate Efficacy of Silmitasertib Plus Gemcitabine and Cisplatin Combination Treatment for Cholangiocarcinoma
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United States , John Soong , Senhwa Biosciences , American Society , ஒன்றுபட்டது மாநிலங்களில் , ஜான் சூங் , அமெரிக்கன் சமூகம் ,

Senhwa Announces the First Patient Enrolled in an Investigator Initiated Trial Of Silmitasertib as a Treatment for Patients with Severe COVID-19


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TAIPEI and SAN DIEGO, Jan. 21, 2021 /PRNewswire/ Senhwa Biosciences, Inc. (TPEx: 6492), a clinical-stage biopharmaceutical company focused on next generation DNA Damage Response (DDR) therapeutics for the treatment of cancer, today announced that the first patient has enrolled into an investigator-initiated trial (IIT) of its investigational drug, Silmitasertib, as a treatment for hospitalized COVID-19 patients at Banner Health-University Medical Center in Phoenix, Arizona (BUMCP).
This IIT is a Phase II multi-center, open-label, randomized, controlled interventional prospective study. BUMCP intends to enroll 40 patients with severe COVID-19, where half will receive Silmitasertib for 14 days. Senhwa s Silmitasertib is an oral medication, targeting the host protein kinase CK2 (casein kinase 2), where virus mutations are unlikely to affect its anti-viral and anti-inflammatory efficacy. It is thought that Silmitasertib challenges ....

United States , T Ai Pei , San Diego , University Medical Center , John Soong , Glassberg Csete , Senhwa Biosciences , Marilyn Glassberg Csete , Senhwa Silmitasertib , Chris Recknor , Esa Rayyan , Senhwa Biosciences Inc , Banner Health , Prnewswire Senhwa Biosciences Inc , Banner Health University Medical Center , Principle Investigator , Chief Medical Officer , Advanced Research , Orphan Drug Designation , Rare Pediatric Disease Designation , ஒன்றுபட்டது மாநிலங்களில் , டி ஐ பேய் , சான் டியாகோ , பல்கலைக்கழகம் மருத்துவ மையம் , ஜான் சூங் , ஏச றாய்யான் ,

Senhwa Biosciences Receives US FDA 'Study May Proceed' Letter to Treat BRCA2+ or PALB2+ Solid Tumors With CX-5461


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TAIPEI and SAN DIEGO, Dec. 23. 2020 /PRNewswire/ Senhwa Biosciences, Inc. (TPEx: 6492), a clinical-stage biopharmaceutical company focused on next-generation DNA Damage Response (DDR) therapeutics for the treatment of cancer, today announced that it has received a Study May Proceed letter from the US Food and Drug Administration (FDA) to begin a Phase Ib study evaluating CX-5461, a first-in-class G-quadruplex stabilizer, to treat solid tumors with
BRCA2 or
PALB2 mutations.
The FDA s approval of our Phase Ib clinical trial application for testing CX-5461 in patients with
BRCA2 or
PALB2 mutations is an important milestone and marks a new paradigm in the treatment of cancers with specific pathogenic mutations, stated Dr. John Soong, the Chief Medical Officer of Senhwa Biosciences. ....

T Ai Pei , United States , San Diego , John Soong , Senhwa Biosciences , Senhwa Bioscience , Tai Sen Soong , Canadian Cancer Trial Group , Drug Administration , Prnewswire Senhwa Biosciences Inc , Senhwa Biosciences Inc , Cancer Dream Team Grant , Prostate Cancer Foundation , Health Canada , Chief Medical Officer , Dream Team Grant , Pfizer Global Challenge Award , Homologous Recombination , Homologous Recombination Deficiency , டி ஐ பேய் , ஒன்றுபட்டது மாநிலங்களில் , சான் டியாகோ , ஜான் சூங் , தை சென் சூங் , கனடியன் புற்றுநோய் சோதனை குழு , புற்றுநோய் கனவு அணி மானியம் ,