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Top News In ஜான்சன் புற்றுநோய் மையம் Today - Breaking & Trending Today

Eliminating RNA-binding protein improves survival in aggressive leukemia

Scientists find that removing IGF2BP3 selectively targets cancer cells while leaving healthy cells alone
UCLA Broad Stem Cell Research Center
Dr. Dinesh Rao and his colleagues had previously identified the IGF2BP3 protein as a factor in driving the development of leukemia through its regulation of RNA messages.
Denise Heady |
July 28, 2021
Removing a protein that is often overexpressed in a rare and aggressive subtype of leukemia can help to slow the cancer’s development and significantly increase the likelihood of survival, according to a study in mice led by scientists at the UCLA Jonsson Comprehensive Cancer Center.
The research, published today in the journal Leukemia, could aid in the development of targeted therapies for cancers that have high levels of the RNA-binding protein IGF2BP3 especially acute lymphoblastic and myeloid leukemias that are characterized by chromosomal rearrangements in the mixed lineage leukemia (MLL) gene. ....

Jeremy Sanford , Jennifer King , Jaspal Bassi , Jolene Draper , Tiffany Tran , Dinesh Rao , Sol Katzman , Oscar Silva , Amit Jaiswal , Neha Nibber , Julia Philipp , Jayanth Palanichamy , Tasha Lin , Stem Cell Research , David Geffen School Of Medicine , Jonsson Cancer Center , National Institutes Of Health , Jonsson Comprehensive Cancer Center , Stanford University , Edythe Broad Center , Comprehensive Cancer , David Geffen School , Regenerative Medicine , Stem Cell , May Paing , National Institutes ,

Removing RNA-binding protein in subtype of leukemia can help to slow the cancer's development

Removing RNA-binding protein in subtype of leukemia can help to slow the cancer s development
Removing a protein that is often overexpressed in a rare and aggressive subtype of leukemia can help to slow the cancer s development and significantly increase the likelihood of survival, according to a study in mice led by scientists at the UCLA Jonsson Comprehensive Cancer Center.
The research, published in the journal Leukemia, could aid in the development of targeted therapies for cancers that have high levels of the RNA-binding protein IGF2BP3 -; especially acute lymphoblastic and myeloid leukemias that are characterized by chromosomal rearrangements in the mixed lineage leukemia (MLL) gene. ....

Jeremy Sanford , Jennifer King , Jaspal Bassi , Jolene Draper , Tiffany Tran , Dinesh Rao , Emily Henderson , Sol Katzman , Oscar Silva , Amit Jaiswal , Neha Nibber , Julia Philipp , Jayanth Palanichamy , Tasha Lin , Stem Cell Research , David Geffen School Of Medicine , Jonsson Cancer Center , National Institutes Of Health , Jonsson Comprehensive Cancer Center , Stanford University , Edythe Broad Center , Comprehensive Cancer , David Geffen School , Regenerative Medicine , Stem Cell , May Paing ,

Eliminating RNA-binding protein improves survival in aggressive leukemia

Eliminating RNA-binding protein improves survival in aggressive leukemia
scienceblog.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from scienceblog.com Daily Mail and Mail on Sunday newspapers.

Jeremy Sanford , Jennifer King , Jaspal Bassi , Jolene Draper , Tiffany Tran , Dinesh Rao , Sol Katzman , Oscar Silva , Amit Jaiswal , Neha Nibber , Julia Philipp , Jayanth Palanichamy , Tasha Lin , Stem Cell Research , David Geffen School Of Medicine , Jonsson Cancer Center , National Institutes Of Health , Jonsson Comprehensive Cancer Center , Stanford University , Edythe Broad Center , Comprehensive Cancer , David Geffen School , Regenerative Medicine , Stem Cell , May Paing , National Institutes ,

Scientists provide new insight on how to stop transcription of cancer cells

Scientists provide new insight on how to stop transcription of cancer cells
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Michael Carey , Fei Sun , Michael Kronenberg , Chengyang Huang , Terrence Sun , Stem Cell Research , Shantou University Medical College , David Geffen School Of Medicine , Jonsson Cancer Center , Jonsson Comprehensive Cancer Center , Gene Regulation Program , Genes Development , Edythe Broad Center , Comprehensive Cancer Center , Biological Chemistry , Jonsson Cancer , Regenerative Medicine , Stem Cell , David Geffen School , Xianglong Tan , Shantou University Medical , மைக்கேல் கேரி , ஃபெ சூரியன் , மைக்கேல் க்ரோனன்பெர்க் , தண்டு செல் ஆராய்ச்சி , டேவிட் கெஃப்ஃபெந் பள்ளி ஆஃப் மருந்து ,

Tool helps predicts who will respond best to targeted prostate cancer therapy

New ‘nomogram’ opens the door to improved personalized treatments, UCLA-led study shows
UCLA
Based on the study, researchers also created an online risk calculator that forecasts the probability of overall and progression-free survival in response to LuPSMA.
Denise Heady |
July 8, 2021
A new prognostic tool developed by researchers from the UCLA Jonsson Comprehensive Cancer Center and five other institutions helps predict which men with advanced metastatic prostate cancer will respond favorably to a novel targeted therapy.
The tool, described in a study published today in Lancet Oncology, analyzes a wide spectrum of imaging and clinical data and is intended to assist physicians considering treating patients with Lutetium-177 prostate-specific membrane antigen, or LuPSMA. ....

United States , Baden Wüberg , Wolfgang Fendler , Wesley Armstrong , Michael Hofman , Rouzbeh Esfandiari , Uwe Haberkorn , Ebrahim Delpassand , Matthew Rettig , Clemens Kratochwil , Ken Herrmann , Johannes Czernin , David Elashoff , Tristan Grogan , Shahneen Sandhu , Boris Hadaschik , Matthias Eiber , Robert Tauber , Andrei Gafita , David Geffen School Of Medicine , Jonsson Cancer Center , Peter Maccallum Cancer Center , Drug Administration , Jonsson Comprehensive Cancer Center , Essen University Hospital , Heidelberg University Hospital ,