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E-Mail IMAGE: Shareholder value at the end of 2016 compared to IPO for biotech companies and paired controls completing IPOs 1997-2016. Net growth in shareholder value, and the fraction of companies generating. view more Credit: Center for Integration of Science and Industry, Bentley University Investing in biotech companies may not entail higher risk than investing in other sectors, according to a new report from Bentley University s Center for Integration of Science and Industry. A large scale study of biotechnology companies that completed Initial Public Offerings (IPOs) from 1997-2016 demonstrates that these companies produced more than $100 billion in shareholder value and almost $100 billion in new value creation despite a failure rate greater than 50%. The study compared the financial performance and economic value created by these biotech companies to non-biotechnology controls that had similarly timed IPOs. ....