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Merck KGaA, Darmstadt, Germany Announces Update on the INTR@PID Clinical Program Including Lung 037 Study


Not intended for UK-based media
Merck KGaA, Darmstadt, Germany, a leading science and technology company, today announced an update on the Phase III [email protected] Lung 037 study and the extensive [email protected] clinical trial program for the potential first-in-class investigational bifunctional immunotherapy bintrafusp alfa, in difficult-to-treat cancers, including biliary tract cancer (BTC) and cervical cancer.
The comprehensive [email protected] program is designed to assess the impact of bintrafusp alfa across distinct cancers and settings where TGF-β is thought to play a driving role. TGF-β is a cytokine that is known to be associated with tumor propagation and metastatic potential such as local immunosuppression, fibrosis, growth of tumor blood vessels and chemo- or radiotherapy resistance through several mechanisms. Trapping TGF-β in the tumor microenvironment on top of PD-L1 blockade is thought to be transformative in different clinical settings. ....

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Custom Oligos for Commercial Use from The Life Science business of Merck KGaA, Darmstadt, Germany, operates as MilliporeSigma in the U.S. and Canada


Application Area:Amplification of synthesized DNA
Very easy to use, the price is low and quality is high. In addition, it arrives immediately after ordering, so you can do experiments quickly.
Review date: 29 Oct 2020 |
Custom Oligos for Commercial Use
We offer custom custom oligos for life science research tools, molecular diagnostics, and laboratory developed tests. We also perform component or complete kit manufacturing, including custom formulations, packaging, and private labeling. Learn about our manufacturing capabilities or request a consultation to determine which type of product best fits your needs.
Product Overview
Custom Oligos for Commercial Use ....

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Merck acquires AmpTec to expand mRNA capabilities


Industry News: Merck acquires AmpTec to expand mRNA capabilities for vaccines, treatments and diagnostics
Diagnostics business focused on producing customized long RNAs and DNAs for in vitro diagnostics, complements existing Merck portfolio
11 Jan 2021
Merck, a leading science and technology company, has announced the acquisition of AmpTec, a leading Hamburg, Germany-based, mRNA contract development and manufacturing organization (CDMO). The deal strengthens Merck’s capabilities to develop and manufacture mRNA for its customers for use in vaccines, treatments and diagnostics applicable in Covid-19 and many other diseases. Financial terms were not disclosed.
“The success of mRNA-based vaccines for Covid-19 lays the path to accelerate the development of these therapeutics for many other diseases,” said Stefan Oschmann, Chairman of the Executive Board and CEO of Merck. “By combining AmpTec’s PCR-based mRNA technology with Merck’s extensive expertise in lip ....

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