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Britain to test mixing and matching of COVID-19 vaccines, and length of time between doses

Britain to test mixing and matching of COVID-19 vaccines, and length of time between doses
Frank Augstein/AP
FILE - A nurse prepares to administer the Pfizer-BioNTech COVID-19 vaccine at Guyâs Hospital in London, Tuesday, Dec. 8, 2020. U.K. health authorities rolled out the first doses of a widely tested and independently reviewed COVID-19 vaccine Tuesday, starting a global immunization program that is expected to gain momentum as more serums win approval. (AP Photo/Frank Augstein, Pool)
By:
Scripps National & The Associated Press
Posted at 1:33 PM, Feb 04, 2021
and last updated 2021-02-04 14:33:47-05
British scientists are starting a 13-month vaccine trial to test whether COVID-19 vaccines can be mixed and matched. ....

United Kingdom , Oxford University Matthew Snape , National Immunisation Schedule Evaluation Consortium , Oxford University , Matthew Snape , ஒன்றுபட்டது கிஂக்டம் , ஆக்ஸ்ஃபர்ட் பல்கலைக்கழகம் மேத்யூ ஸ்னேப் , தேசிய நோய்த்தடுப்பு அட்டவணை மதிப்பீடு கூட்டமைப்பு , ஆக்ஸ்ஃபர்ட் பல்கலைக்கழகம் , மேத்யூ ஸ்னேப் ,

UK begins world's first alternate dosing Covid-19 vaccine trial

Health chiefs in the UK on Thursday began what they have described as a world-first clinical trial of patients who will receive different COVID-19 vaccines for their first or second dose, to detect its impact on immunity against coronavirus.
The study, backed by 7 million pound of government funding, will determine the effects of using different vaccines for the first and second dose for example, using Oxford University/AstraZeneca s vaccine for the first dose, followed by Pfizer/BioNTech s vaccine for the second.
It is being run by the National Immunisation Schedule Evaluation Consortium (NISEC) across eight National Institute for Health Research (NIHR) supported sites and also gather immunological evidence on different intervals between the first and second dose for a mixed-vaccine regimen against control groups when the same vaccine is used for both doses. ....

United Kingdom , City Of , Oxford Astrazeneca , Jonathan Van Tam , Matthew Snape , Andrew Ustianowski , Nadhim Zahawi , Research Ethics Committee , Oxford University Astrazeneca , University Of Oxford , Committee On Vaccination , Regulatory Agency , Vaccine Research Registry , National Institute For Health Research , Department Of Health , National Immunisation Schedule Evaluation Consortium , National Clinical , Vaccine Research Programme , National Institute , Health Research , Professor Jonathan Van Tam , Deputy Chief Medical Officer , Senior Responsible Officer , Prime Boost , Chief Investigator Matthew Snape , Associate Professor ,

UK Launches 'World First' Trial Mixing Different COVID Vaccines for First, Second Doses – NBC Connecticut

It is hoped the study will help policymakers understand whether mixing different Covid vaccines could be a viable route to increase the flexibility of vaccination programs and whether it could even provide better protection.
If we do show that these vaccines can be used interchangeably in the same schedule this will greatly increase the flexibility of vaccine delivery, and could provide clues as to how to increase the breadth of protection against new virus strains, Matthew Snape, chief investigator on the trial and associate professor in Paediatrics and Vaccinology at the University of Oxford, said on Thursday.
The trial, which is formally known as the COVID-19 Heterologous Prime Boost study but has been dubbed the Com-Cov study, will recruit over 800 volunteers aged 50 and above in England to evaluate the four different combinations of prime and booster vaccination. ....

United Kingdom , Jonathan Van Tam , Matthew Snape , Nadhim Zahawi , Johns Hopkins University , University Of Oxford , University Of Oxford Astrazeneca , National Immunisation Schedule Evaluation Consortium , National Immunisation Schedule Evaluation , Prime Boost , Vaccines Taskforce , Chief Medical Officer , Senior Responsible Officer , Professor Jonathan Van Tam , ஒன்றுபட்டது கிஂக்டம் , ஜொனாதன் வேன் டாம் , மேத்யூ ஸ்னேப் , ஜான்ஸ் ஹாப்கின்ஸ் பல்கலைக்கழகம் , பல்கலைக்கழகம் ஆஃப் ஆக்ஸ்ஃபர்ட் , தேசிய நோய்த்தடுப்பு அட்டவணை மதிப்பீடு கூட்டமைப்பு , தேசிய நோய்த்தடுப்பு அட்டவணை மதிப்பீடு , ப்ரைம் ஊக்க , தலைமை மருத்துவ அதிகாரி , மூத்தவர் பொறுப்பு அதிகாரி , ப்ரொஃபெஸர் ஜொனாதன் வேன் டாம் ,

UK begins world-first alternate dosing covid-19 vaccine trial

UK begins world-first alternate dosing covid-19 vaccine trial
The 13-month study will monitor the impact of the different dosing regimens on patients’ immune responses
(REUTERS)
Aditi Khanna
, PTI
The study, backed by 7 million pound of government funding, will determine the effects of using different vaccines for the first and second dose
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LONDON :
Health chiefs in the UK on Thursday began what they have described as a world-first clinical trial of patients who will receive different COVID-19 vaccines for their first or second dose, to detect its impact on immunity against coronavirus.
The study, backed by 7 million pound of government funding, will determine the effects of using different vaccines for the first and second dose – for example, using Oxford University/AstraZeneca’s vaccine for the first dose, followed by Pfizer/BioNTech’s vaccine for the second. ....

United Kingdom , City Of , Oxford Astrazeneca , Jonathan Van Tam , Matthew Snape , Andrew Ustianowski , Nadhim Zahawi , Research Ethics Committee , Oxford University Astrazeneca , University Of Oxford , Committee On Vaccination , Regulatory Agency , Vaccine Research Registry , National Institute For Health Research , Department Of Health , National Clinical , National Immunisation Schedule Evaluation Consortium , Vaccine Research Programme , National Institute , Health Research , Professor Jonathan Van Tam , Deputy Chief Medical Officer , Senior Responsible Officer , Prime Boost , Chief Investigator Matthew Snape , Associate Professor ,

U.K. study to test giving doses of two different COVID vaccines

U.K. study to test giving doses of two different COVID vaccines
Caitlin O Kane
© Jae C. Hong / AP
Virus Outbreak Congress Letter
A new vaccine trial is underway in the U.K. to test whether mixing and matching different COVID-19 vaccines for the first and second doses is effective, BBC News reports.
The country is currently using the Pfizer-BioNTech vaccine and Oxford-AstraZeneca vaccine, which both require two doses. For the study, run by the National Immunisation Schedule Evaluation Consortium, patients will get one dose of each.
The trial will involve 800 volunteers, age 50 or older, who haven t received a COVID-19 vaccine yet. They will receive their two vaccine doses as usual, four or 12 weeks apart, but one will be the Oxford shot and the other will be the Pfizer shot. If regulators approve other vaccines for use, they may be added to the study. ....

Jonathan Van Tam , Matthew Snape , Nadhim Zahawi , Us Centers For Disease , University Of Oxford , National Immunisation Schedule Evaluation Consortium , Advisory Committee On Immunization Practices , Virus Outbreak Congress Letter , Virus Outbreak Congress , Professor Jonathan Van Tam , Minister Nadhim Zahawi , Advisory Committee , Immunization Practices , Disease Control , ஜொனாதன் வேன் டாம் , மேத்யூ ஸ்னேப் , எங்களுக்கு மையங்கள் க்கு நோய் , பல்கலைக்கழகம் ஆஃப் ஆக்ஸ்ஃபர்ட் , தேசிய நோய்த்தடுப்பு அட்டவணை மதிப்பீடு கூட்டமைப்பு , வைரஸ் ஔட்‌ப்ரேக் காங்கிரஸ் கடிதம் , வைரஸ் ஔட்‌ப்ரேக் காங்கிரஸ் , ப்ரொஃபெஸர் ஜொனாதன் வேன் டாம் , நோய்த்தடுப்பு ப்ர்யாக்டிஸஸ் , நோய் கட்டுப்பாடு ,