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Vela Diagnostics Announces Collaboration with the National Cancer Centre of Singapore to Refine Novel Cancer Therapy


Vela Diagnostics Announces Collaboration with the National Cancer Centre of Singapore to Refine Novel Cancer Therapy
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SINGAPORE, June 3, 2021 /PRNewswire/ Vela Diagnostics announced a collaboration with the National Cancer Centre of Singapore (NCCS) to develop a molecular diagnostic assay to predict individual patients responses to a cancer therapy called Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibitors (TKIs). Being able to predict an individual s response will help clinicians determine if EGFR-TKIs are a suitable therapeutic option for the patient. The partnership between Vela Diagnostics and NCCS aims to refine the therapeutic management of cancer to improve clinical outcomes. ....

Charlie Lee , Gopal Iyer , Head Of Research , National Cancer Centre Of Singapore , Scientist Individual Research Grant , Head Of The Division Medical Sciences , Neck Centre , Division Of Medical Oncology , Singapore Translational Cancer Consortium , Epidemiological Services , National Cancer Centre , Epidermal Growth Factor Receptor , Vela Diagnostics , Nature Medicine , Professor Gopal Iyer , Associate Professor Daniel Tan , Prof Gopal Iyer , Medical Sciences , Senior Consultant , Assoc Prof Daniel Tan , Deputy Head , Clinical Trials , Medical Oncology , Singapore Ministry , National Medical Research Council , Clinician Scientist Individual Research Grant ,

New study launched to more accurately diagnose early hepatocellular carcinoma


New study launched to more accurately diagnose early hepatocellular carcinoma
A first of its kind cohort study on patients at high risk of developing primary liver cancer also known as hepatocellular carcinoma (HCC), has been launched to diagnose HCC more accurately at an earlier stage and to predict an individual s likelihood of developing the cancer. HCC is the sixth most common cancer in the world but the third most common cause of cancer deaths globally. In Singapore, HCC is the third and fourth most common cause of cancer deaths, amongst males and females respectively.
While potentially curative treatment is possible with early diagnosis, only 20% of HCC cases are detected at a stage where cure is possible. This investigator-initiated multi-centre study led by the National Cancer Centre of Singapore (NCCS) called EarLy DEtection of HCC: miRNA, microbiome and imaGing biomArkers in the evolution of chroNiC livEr Disease in a high-risk prospective cohort (ELEGANCE), addr ....

National University Hospital , Singapore General , Marine Parade , Tan Tock Seng Hospital , Bukit Merah , Mihir Gandhi , Asia Pacific , Wang Yulan , Emily Henderson , Dan Yock Young , Jason Chang Pik , Centre For Quantitative Medicine , Division Of Gastroenterology , Agency Of Science , Lee Kong Chian School Of Medicine , National Cancer Centre Of Singapore , Nanyang Technological University Singapore , Singapore Phenome Centre , Department Of Gastroenterology Hepatology , National Cancer Centre Singapore , Division Of Surgery , Health Services Systems Research Signature Programme , National Cancer Centre , Pierce Chow , Principal Investigator , Senior Consultant ,

Landmark study launched to detect liver cancer early in Singapore


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IMAGE: Quantitative MR images of the liver from six patients presenting with liver cancer produced by Perspectum s LiverMultiScan which will be used in a new study led by National Cancer Centre.
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Credit: Image credit: Mole DJ et al. Plos One. 2020;15(12):e0238568
Only 20% of primary liver cancer or hepatocellular carcinoma (HCC) are diagnosed at an early stage, which makes early detection an urgent, unmet healthcare need.
Study aims to develop more accurate diagnostics for early HCC, an AI algorithm to predict an individual s risk of developing HCC, and discover novel molecular targets to prevent the development of HCC. ....

National University Hospital , Singapore General , Marine Parade , Tan Tock Seng Hospital , Bukit Merah , National University Of Singapore , City Of , United Kingdom , Dharshini Subbiah , Shireen Federico , Dan Yock Young , Wang Yulan , Jason Chang Pik , Mihir Gandhi , Asia Pacific , Perspectum Livermultiscan , Yu Zehan , Duke University School Of Medicine , National Registry Of Diseases Office , Nanyang Technological University , Agency Of Science , Lee Kong Chian School Of Medicine , National Institute Of Education , Department Of Gastroenterology Hepatology , Singapore Centre For Environmental Life Sciences Engineering , Division Of Surgery ,