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Singapore discovers brain enzyme that activates dormant neural stem cells

Singapore discovers brain enzyme that activates dormant neural stem cells
Singapore discovers brain enzyme that activates dormant neural stem cells
12 February 2021 | News
Photo Credit: Freepik
Singapore s Duke-NUS Medical School researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant ‘quiescent’ state, enabling them to proliferate and generate new neurons. Published in the journal
EMBO Reports, the study could help clarify how some neurodevelopmental disorders such as autism and microcephaly occur.
Pr-set7 is an enzyme involved in maintaining genome stability, DNA repair and cell cycle regulation, as well as turning various genes on or off. This protein, which goes by a few different names, has remained largely unchanged as species have evolved. Professor Wang Hongyan, a professor and deputy director at Duke-NUS’ Neuroscience and Behavioural Disorders Program ....

Wang Hongyan , Behavioural Disorders Programme , European Molecular Biology Organization , Prof Wang , Associate Member , Wake Up Call For Neural Stem Cells , நடத்தை கோளாறுகள் ப்ரோக்ராம் , ஐரோப்பிய மூலக்கூறு உயிரியல் ஆர்கநைஸேஶந் , ப்ரொஃப் வாங் , இணை உறுப்பினர் , எழுந்திரு மேலே அழைப்பு க்கு நரம்பியல் தண்டு செல்கள் ,

A brain enzyme plays an important role in waking up neural stem cells

A brain enzyme plays an important role in waking up neural stem cells
Researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant quiescent state, enabling them to proliferate and generate new neurons. Published in the journal EMBO Reports, the study by Duke-NUS Medical School, Singapore, could help clarify how some neurodevelopmental disorders such as autism and microcephaly occur.
Quiescent neural stem cells in the fruit fly larval brainPr-set7 is an enzyme involved in maintaining genome stability, DNA repair and cell cycle regulation, as well as turning various genes on or off. This protein, which goes by a few different names, has remained largely unchanged as species have evolved. Professor Wang Hongyan, a professor and deputy director at Duke-NUS Neuroscience and Behavioural Disorders Programme, and her colleagues set out to understand the protein s function during brain development ....

Wang Hongyan , Patrick Casey , Emily Henderson , Dean For Research At , Behavioural Disorders Programme , Senior Vice Dean , Professor Wang , Neural Stem Cells , Stem Cells , Medical School , பேட்ரிக் வழக்கு , எமிலி ஹென்டர்சன் , டீன் க்கு ஆராய்ச்சி இல் , நடத்தை கோளாறுகள் ப்ரோக்ராம் , மூத்தவர் துணை டீன் , ப்ரொஃபெஸர் வாங் , நரம்பியல் தண்டு செல்கள் , தண்டு செல்கள் , மன இறுக்கம் , மருத்துவ பள்ளி ,

Wake-up call for neural stem cells

A brain enzyme activates dormant neural stem cells, revealing how defects in its gene could lead to neurodevelopmental disorders. ....

Wang Hongyan , Patrick Casey , Dean For Research At , Behavioural Disorders Programme , European Molecular Biology Organization , Senior Vice Dean , Professor Wang , Prof Wang , Associate Member , பேட்ரிக் வழக்கு , டீன் க்கு ஆராய்ச்சி இல் , நடத்தை கோளாறுகள் ப்ரோக்ராம் , ஐரோப்பிய மூலக்கூறு உயிரியல் ஆர்கநைஸேஶந் , மூத்தவர் துணை டீன் , ப்ரொஃபெஸர் வாங் , ப்ரொஃப் வாங் , இணை உறுப்பினர் ,