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Blocking IL-11 signalling can help liver regenerate after injury from paracetamol toxicity

Blocking IL-11 signalling can help liver regenerate after injury from paracetamol toxicity
asiaresearchnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from asiaresearchnews.com Daily Mail and Mail on Sunday newspapers.

United Kingdom , Anissa Widjaja , Patrick Casey , Enleofen Bio , Stuart Cook , National Heart Centre Singapore , Department Of Cardiology , Tanoto Foundation Professor Of Cardiovascular Medicine , Dean For Research At , Boehringer Ingelheim , National Advisory Committee For Laboratory Animal Research , Academic Medical Centre , Science Translational Medicine , Assistant Professor Anissa Widjaja , Metabolic Diseases , National Advisory Committee , Laboratory Animal Research , Professor Stuart Cook , Tanoto Foundation Professor , Cardiovascular Medicine , Medical Centre , Senior Consultant , Prof Cook , Singapore Based Enleofen Bio , Senior Vice Dean , ஒன்றுபட்டது கிஂக்டம் ,

Researchers discover molecule that provides dual protection against vascular inflammation

Researchers discover molecule that provides dual protection against vascular inflammation
A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A STAR) in Singapore discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity. The study, published in the journal
Nature Communications, revealed how one gene encoded two molecules that provide two-pronged protection following viral infection.
Chronic and excessive inflammation of the blood vessels, known as vascular inflammation, can lead to tissue damage and cardiovascular diseases such as atherosclerosis and fibrosis. Although some therapies have shown promising results in clinical trials, they have considerable side effects, such as immunosuppression leading to increased risk of infection, and limited efficacy. Therefore, more effective treatments are urgently needed. ....

Patrick Casey , Emily Henderson , Owen Rackham , Agency For Science , Metabolic Diseases Programme At , Nature Communications , Institute Of Molecular , Dean For Research At , Senior Research Fellow Dr Cheryl Lee , Metabolic Diseases Programme , Associate Professor Ashley St John , Assistant Professor Owen Rackham , Senior Research Fellow Dr Cheryl , Cell Biology , Assoc Prof St John , Asst Prof , Senior Vice Dean , பேட்ரிக் வழக்கு , எமிலி ஹென்டர்சன் , ஓவந் ராக்ஹாம் , இயற்கை தகவல்தொடர்புகள் , நிறுவனம் ஆஃப் மூலக்கூறு , டீன் க்கு ஆராய்ச்சி இல் , இணை ப்ரொஃபெஸர் ஆஷ்லே ஸ்டம்ப் ஜான் , உதவியாளர் ப்ரொஃபெஸர் ஓவந் ராக்ஹாம் , செல் உயிரியல் ,

Newly-discovered molecule provides dual protection against vascular inflammation

Newly-discovered molecule provides dual protection against vascular inflammation
asiaresearchnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from asiaresearchnews.com Daily Mail and Mail on Sunday newspapers.

Patrick Casey , Owen Rackham , Agency For Science , Nature Communications , Institute Of Molecular , Dean For Research At , Senior Research Fellow Dr Cheryl Lee , Metabolic Disorders Programme At , Metabolic Disorders Programme , Associate Professor Ashley St John , Assistant Professor Owen Rackham , Senior Research Fellow Dr Cheryl , Cell Biology , Assoc Prof St John , Asst Prof , Senior Vice Dean , பேட்ரிக் வழக்கு , ஓவந் ராக்ஹாம் , இயற்கை தகவல்தொடர்புகள் , நிறுவனம் ஆஃப் மூலக்கூறு , டீன் க்கு ஆராய்ச்சி இல் , வளர்சிதை மாற்ற கோளாறுகள் ப்ரோக்ராம் இல் , வளர்சிதை மாற்ற கோளாறுகள் ப்ரோக்ராம் , இணை ப்ரொஃபெஸர் ஆஷ்லே ஸ்டம்ப் ஜான் , உதவியாளர் ப்ரொஃபெஸர் ஓவந் ராக்ஹாம் , செல் உயிரியல் ,

Strong and balanced T cell response: key to controlling SARS-CoV-2 infection without getting COVID-19

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To effectively fight off SARS-CoV-2, the immune system depends on both antibodies and T cells, a type of white blood cell, which work together to eradicate the virus. However, little was known about virus-specific T cells in asymptomatic patients.
We now know that many people are getting infected with SARS-CoV-2 without realising it, as they stay healthy and don t develop any symptoms. These asymptomatic infections may provide the key to understanding how the immune system can control the virus without triggering pathological processes, explained Dr Nina Le Bert, Senior Research Fellow at the Duke-NUS Emerging Infectious Diseases (EID) Programme and the co-author of this study. ....

National University Hospital , Singapore General , Nina Le Bert , Patrick Casey , Clarencec Tam , Antonio Bertoletti , Senior Research , Dean For Research At , National Centre For Infectious Diseases , Swee Hock School Of Public Health , Senior Research Fellow , Emerging Infectious Diseases , Assistant Professor Clarence , Swee Hock School , Public Health , Singapore General Hospital , National Centre , Professor Antonio Bertoletti , Professor Patrick Casey , Senior Vice Dean , Medicine Health , Infectious Emerging Diseases , தேசிய பல்கலைக்கழகம் மருத்துவமனை , சிங்கப்பூர் ஜநரல் , நினா லெ பெர்ட் , பேட்ரிக் வழக்கு ,

A brain enzyme plays an important role in waking up neural stem cells

A brain enzyme plays an important role in waking up neural stem cells
Researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant quiescent state, enabling them to proliferate and generate new neurons. Published in the journal EMBO Reports, the study by Duke-NUS Medical School, Singapore, could help clarify how some neurodevelopmental disorders such as autism and microcephaly occur.
Quiescent neural stem cells in the fruit fly larval brainPr-set7 is an enzyme involved in maintaining genome stability, DNA repair and cell cycle regulation, as well as turning various genes on or off. This protein, which goes by a few different names, has remained largely unchanged as species have evolved. Professor Wang Hongyan, a professor and deputy director at Duke-NUS Neuroscience and Behavioural Disorders Programme, and her colleagues set out to understand the protein s function during brain development ....

Wang Hongyan , Patrick Casey , Emily Henderson , Dean For Research At , Behavioural Disorders Programme , Senior Vice Dean , Professor Wang , Neural Stem Cells , Stem Cells , Medical School , பேட்ரிக் வழக்கு , எமிலி ஹென்டர்சன் , டீன் க்கு ஆராய்ச்சி இல் , நடத்தை கோளாறுகள் ப்ரோக்ராம் , மூத்தவர் துணை டீன் , ப்ரொஃபெஸர் வாங் , நரம்பியல் தண்டு செல்கள் , தண்டு செல்கள் , மன இறுக்கம் , மருத்துவ பள்ளி ,