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Researchers discover molecule that provides dual protection against vascular inflammation


Researchers discover molecule that provides dual protection against vascular inflammation
A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A STAR) in Singapore discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity. The study, published in the journal
Nature Communications, revealed how one gene encoded two molecules that provide two-pronged protection following viral infection.
Chronic and excessive inflammation of the blood vessels, known as vascular inflammation, can lead to tissue damage and cardiovascular diseases such as atherosclerosis and fibrosis. Although some therapies have shown promising results in clinical trials, they have considerable side effects, such as immunosuppression leading to increased risk of infection, and limited efficacy. Therefore, more effective treatments are urgently needed. ....

Patrick Casey , Emily Henderson , Owen Rackham , Agency For Science , Metabolic Diseases Programme At , Nature Communications , Institute Of Molecular , Dean For Research At , Senior Research Fellow Dr Cheryl Lee , Metabolic Diseases Programme , Associate Professor Ashley St John , Assistant Professor Owen Rackham , Senior Research Fellow Dr Cheryl , Cell Biology , Assoc Prof St John , Asst Prof , Senior Vice Dean , பேட்ரிக் வழக்கு , எமிலி ஹென்டர்சன் , ஓவந் ராக்ஹாம் , இயற்கை தகவல்தொடர்புகள் , நிறுவனம் ஆஃப் மூலக்கூறு , டீன் க்கு ஆராய்ச்சி இல் , இணை ப்ரொஃபெஸர் ஆஷ்லே ஸ்டம்ப் ஜான் , உதவியாளர் ப்ரொஃபெஸர் ஓவந் ராக்ஹாம் , செல் உயிரியல் ,

Singapore finds molecule for dual protection against vascular inflammation


Singapore finds molecule for dual protection against vascular inflammation
Singapore finds molecule for dual protection against vascular inflammation
23 April 2021 | News
Image credit- shutterstock.com
A multidisciplinary team of researchers from Duke-NUS Medical School and the Agency for Science, Technology and Research (A STAR) in Singapore has discovered a new mitochondrial peptide called MOCCI that plays an important role in regulating inflammation of blood vessel and immunity.
The study, published in the journal 
Nature Communications, revealed how one gene encoded two molecules that provide two-pronged protection following viral infection.
“In this study, we aimed to identify new targets to combat inflammation in the lining of blood vessels. Specifically, we wanted to target small naturally-produced peptides that have not been studied before,” explained Assistant Professor Lena Ho, from the Cardiovascular and Metabolic Disorders Progra ....

Owen Rackham , Agency For Science , Nature Communications , Senior Research Fellow Dr Cheryl Lee , Metabolic Disorders Programme At , Metabolic Disorders Programme , Associate Professor Ashley St John , Assistant Professor Owen Rackham , Senior Research Fellow Dr Cheryl , Assoc Prof St John , ஓவந் ராக்ஹாம் , இயற்கை தகவல்தொடர்புகள் , வளர்சிதை மாற்ற கோளாறுகள் ப்ரோக்ராம் இல் , வளர்சிதை மாற்ற கோளாறுகள் ப்ரோக்ராம் , இணை ப்ரொஃபெஸர் ஆஷ்லே ஸ்டம்ப் ஜான் , உதவியாளர் ப்ரொஃபெஸர் ஓவந் ராக்ஹாம் ,