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Sex differences play roles in how patients respond to brain diseases

Sex differences play roles in how patients respond to brain diseases
Men and women are impacted differently by brain diseases, like Alzheimer s disease and Parkinson s disease. Researchers are urging their colleagues to remember those differences when researching treatments and cures.
In APL Bioengineering, by AIP Publishing, University of Maryland scientists highlight a growing body of research suggesting sex differences play roles in how patients respond to brain diseases, as well as multiple sclerosis, motor neuron disease, and other brain ailments.
That is progress from just a few years ago, said Alisa Morss Clyne, director of the university s Vascular Kinetics Laboratory. ....

Alisa Morss Clyne , Emily Henderson , Vascular Kinetics Laboratory , University Of Maryland , Vascular Kinetics , Alzheimer 39s Disease , Motor Neuron Disease , Multiple Sclerosis , Parkinson 39s Disease , எமிலி ஹென்டர்சன் , வாஸ்குலர் கிநெடிக்ஸ் ஆய்வகம் , பல்கலைக்கழகம் ஆஃப் மேரிலாந்து , வாஸ்குலர் கிநெடிக்ஸ் , மோட்டார் நரம்பியல் நோய் , பல ஸ்க்லரோசிஸ் ,

Researchers provide complete clinical landscape for gene linked to epilepsy and autism

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Philadelphia, March 17, 2021 - Researchers from Children s Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism. By linking clinical features to genetic abnormalities in a standardized format, the researchers hope their findings lead to improved identification and clinical intervention.
The study was published online by the journal
Genetics in Medicine.
Pathogenic variants in the SCN2A gene can lead to a wide range of clinical features - or phenotypes - associated with neurodevelopmental disorders. Several studies have described the genetic information collected on individuals with disease-causing changes in this gene. However, while genetic information is collected in a standardized manner, data on ph ....

United States , Ingo Helbig , Human Development , Epilepsy Syndrome Consortium , National Center , Institute For Translational Medicine , International League Against Epilepsy , Epilepsy Neurogenetics Initiative , Research Center , Clinical Phd Academy , Research Unit , Innovation Network , Genomics Research , German Research Foundation , National Institute For Neurological Disorders , Chartwell Foundation , Neurogenetics Initiative , Human Phenotype Ontology , National Institute , Neurological Disorders , Channelopathy Associated Research Center , Eunice Kennedy Shriver National Institute , Child Health , Advancing Translational Sciences , National Institutes , Translational Medicine ,

Leading change researchers say it's time workplaces "embraced mess" caused by COVID-19

The Change Lab
17 March 2021
A group of global change experts are sending a disruptive message out to Australian businesses calling for approaches that ’embrace uncertainty and the mess’ of change over trying to “command and control” when it comes to workplace challenges.
The Change Lab are the leading industry experts in helping organisations worldwide (including clients such as Deloitte’s, IBM, LendLease, Treasury Wine Estate, the Dubai Government, Melbourne University and Xero) to thrive through change using the latest research in neuroscience, positive psychology and systems design.
Co-Founder of The Change Lab, Michelle Etheve, says a ‘command and control’ or ‘traditional management’ approach to change in the workplace in the pandemic-impacted landscape won’t work to create the kind of ongoing positive change needed for organisations to operate effectively in the current market context. ....

United Arab Emirates , Michelle Etheve , Michelle Mcquaid , Melbourne University , Xchange Lab , Treasury Wine Estate , Dubai Government , Mental Health , Well Being , Covid 19 , ஒன்றுபட்டது அரபு அமீரகங்கள் , மைக்கேல் மக்வேட் , மெல்போர்ன் பல்கலைக்கழகம் , மாற்றம் ஆய்வகம் , கருவூலம் மது எஸ்டேட் , துபாய் அரசு , மன ஆரோக்கியம் , நன்றாக இருப்பது , சர்வதேச பரவல் ,

Researchers identify several factors that prevent use of sEMG in clinical neurorehabilitation

Researchers identify several factors that prevent use of sEMG in clinical neurorehabilitation
Kessler Foundation researchers have identified several practical and technical barriers to the widespread use of surface electromyography (sEMG) in clinical neurorehabilitation. Based on their holistic analysis of these factors, the researchers suggest a collaborative, interdisciplinary, and unified approach to enable rehabilitation professionals to routinely use sEMG. The article, Use of Surface EMG in Clinical Rehabilitation of Individuals With SCI: Barriers and Future Considerations (doi: 10.3389/fneur.2020.578559), was published December 18, 2020, in
Frontiers in Neurology. It is available open access at https:/
/
PMC7780850/
The authors are Rakesh Pilkar, PhD, Kamyar Momeni, PhD, Arvind Ramanujam, Manikandan Ravi, Erica Garbarini, and Gail F. Forrest, PhD, affiliated with the Center for Mobility and Rehabilitation Engineering Research and the Tim and Caroline R ....

Gailf Forrest , Erica Garbarini , Rakesh Pilkar , Arvind Ramanujam , Manikandan Ravi , Emily Henderson , Kessler Foundation , Rehabilitation Engineering Research , Caroline Reynolds Center , Stimulation At Kessler Foundation , Senior Research Scientist , Clinical Rehabilitation , Individuals With , Kamyar Momeni , Spinal Stimulation , Rehabilitation Engineering , எரிகா கற்பாரினி , அரவிந்த் ராமானுஜம் , மாணிகண்டான் ரவி , எமிலி ஹென்டர்சன் , கெஸ்லர் அடித்தளம் , புனர்வாழ்வு பொறியியல் ஆராய்ச்சி , கரோலின் ரெனால்ட்ஸ் மையம் , ஸ்டிம்யுலேஶந் இல் கெஸ்லர் அடித்தளம் , மூத்தவர் ஆராய்ச்சி விஞ்ஞானி , மருத்துவ புனர்வாழ்வு ,

Pressure sensors could ensure a proper helmet fit to help protect the brain

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IMAGE: When worn under a helmet, a fit cap reveals the pressure exerted by the helmet on 16 different sensors.
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Credit: Adapted from
2021, DOI: 10.1021/acssensors.0c02122
Many athletes, from football players to equestrians, rely on helmets to protect their heads from impacts or falls. However, a loose or improperly fitted helmet could leave them vulnerable to traumatic brain injuries (TBIs), a leading cause of death or disability in the U.S. Now, researchers reporting in
ACS Sensors have developed a highly sensitive pressure sensor cap that, when worn under a helmet, could help reveal whether the headgear is a perfect fit. ....

United States , Western Michigan University , Massood Atashbar , Simin Masihi , Us Congress , Michigan University , Us Centers For Disease , Michigan Corporate Relations Network , American Chemical Society , Disease Control , Advanced Smart Sensors , Western Michigan , Biomedical Environmental Chemical Engineering , Chemistry Physics Materials Sciences , Trauma Injury , Sports Medicine , Sports Recreation , ஒன்றுபட்டது மாநிலங்களில் , மேற்கு மிச்சிகன் பல்கலைக்கழகம் , எங்களுக்கு காங்கிரஸ் , மிச்சிகன் பல்கலைக்கழகம் , எங்களுக்கு மையங்கள் க்கு நோய் , மிச்சிகன் பெருநிறுவன உறவுகள் வலைப்பின்னல் , அமெரிக்கன் இரசாயன சமூகம் , நோய் கட்டுப்பாடு , மேற்கு மிச்சிகன் ,