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Researchers identify new strategy to protect offspring from prenatal stress

Researchers identify new strategy to protect offspring from prenatal stress
New research from the University of Iowa and University Hospitals Cleveland Medical Center demonstrates that offspring can be protected from the effects of prenatal stress by administering a neuroprotective compound during pregnancy.
Working in a mouse model, Rachel Schroeder, a student in the UI Interdisciplinary Graduate Program in Neuroscience, drew a connection between the work of her two mentors, Hanna Stevens, MD, PhD, UI associate professor of psychiatry and Ida P. Haller Chair of Child and Adolescent Psychiatry, and Andrew A. Pieper, MD, PhD, a former UI faculty member, now Morley-Mather Chair of Neuropsychiatry at Case Western Reserve University and Investigator and Director of the Neurotherapeutics Center at the Harrington Discovery Institute, University Hospitals Cleveland Medical Center. ....

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Imaging zebrafish movements in 3D to better understand ALS disease

Credit: Christian Fleury (INRS)
An interdisciplinary team of the Institut national de la recherche scientifique (INRS) used an innovative imaging technique for a better understanding of motor deficits in Amyotrophic Lateral Sclerosis (ALS). The researchers were able to follow the escape behaviour of normal and disease zebrafish models, in 3D. Their results have recently been published in
Optica, the flagship journal of the Optical Society (OSA).
Professor Jinyang Liang, expert in ultra-fast imaging and biophotonics, joined an effort with Professor Kessen Patten, specialist in genetics and neurodegenerative diseases. The two groups were able to track the position of zebrafish in real time and capture the 3D motion, using a special imaging technique called dispersion-eliminated coded-aperture light field, or DECALF. ....

Kessen Patten , Armand Frappier Sant , Jingdan Liu , Charlotte Zaouter , Shunmooguma Patten , Xianglei Liu , Terre Environnement , Jinyang Liang , Anna Sforza Djoukhadjian Research , Optical Society , Engineering Research Council Of Canada , Natural Sciences , Canada Foundation For Innovation , Amyotrophic Lateral Sclerosis , Professor Kessen Patten , Professor Liang , Engineering Research Council , Canada Foundation , Fonds De Recherche , Anna Sforza Djoukhadjian Research Chair , Quebec City , Eau Terre Environnement , Urbanisation Culture Soci , Chemistry Physics Materials Sciences , Medicine Health , ஆர்மண்ட் ப்றப்பிேர் சந்த் ,

Insomnia patients commonly underestimate their actual sleep behavior

Insomnia patients commonly underestimate their actual sleep behavior
People with sleep disorders commonly have a misperception about their actual sleep behavior. A research group led by Karin Trimmel and Stefan Seidel from MedUni Vienna s Department of Neurology (Outpatient Clinic for Sleep Disorders and Sleep-Related Disorders) analyzed polysomnography results to identify the types of sleep disorder that are associated with a discrepancy between self-reported and objective sleep parameters and whether there are any factors that influence this.
The main finding: irrespective of age, gender or screening setting, insomnia patients are most likely to underestimate how long they sleep. The study has been published in the highly regarded ....

Stefan Seidel , Karin Trimmel , Emily Henderson , Meduni Vienna , Outpatient Clinic , Sleep Disorders , Sleep Related Disorders , Clinical Sleep , Sleep Disorder , ஸ்டீபன் சீடல் , எமிலி ஹென்டர்சன் , ஔட்‌ப்யாஶஂட் சிகிச்சையகம் , தூங்கு கோளாறுகள் , தூங்கு தொடர்புடையது கோளாறுகள் , மருத்துவ தூங்கு , தூங்கு கோளாறு ,

Iowa and Ohio team finds strategy to protect developing brain from prenatal stress in mice

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New research from the University of Iowa and University Hospitals Cleveland Medical Center demonstrates that offspring can be protected from the effects of prenatal stress by administering a neuroprotective compound during pregnancy.
Working in a mouse model, Rachel Schroeder, a student in the UI Interdisciplinary Graduate Program in Neuroscience, drew a connection between the work of her two mentors, Hanna Stevens, MD, PhD, UI associate professor of psychiatry and Ida P. Haller Chair of Child and Adolescent Psychiatry, and Andrew A. Pieper, MD, PhD, a former UI faculty member, now Morley-Mather Chair of Neuropsychiatry at Case Western Reserve University and Investigator and Director of the Neurotherapeutics Center at the Harrington Discovery Institute, University Hospitals Cleveland Medical Center. ....

University Of Iowa Health Care , United States , Iowa City , University Of Iowa , Case Western Reserve University , Facebook Universityhospitals , Andrewa Pieper , Shanna Stevens , Preethy Sridharan , Kavithap Kettimuthu , Alexandra Loren , Gordon Evie Safran , Lynn Nguyen , Noelles Williams , Idap Haller , Rachel Schroeder , Louis Stokes Va Medical Center , Harrington Discovery Institute At University Hospitals , Nellie Ball , University Hospitals Cleveland Medical Center , Pieper Lab , Elizabeth Ring Mather William Gwinn Fund , University Of Iowa Physicians , Ui Interdisciplinary Graduate Program In Neuroscience , University Of Texas Southwestern Medical Center , University Hospitals Rainbow Babies Children Hospital ,

Neural network models mimic the behavior of real dendrites

Neural network models mimic the behavior of real dendrites
Neurons, the fundamental units of the brain, are complex computers by themselves. They receive input signals on a tree-like structure - the dendrite. This structure does more than simply collect the input signals: it integrates and compares them to find those special combinations that are important for the neurons role in the brain.
Moreover, the dendrites of neurons come in a variety of shapes and forms, indicating that distinct neurons may have separate roles in the brain.
A simple yet faithful model
In neuroscience, there has historically been a tradeoff between a model s faithfulness to the underlying biological neuron and its complexity. Neuroscientists have constructed detailed computational models of many different types of dendrites. ....

Willem Wybo , Walter Senn , Thomas Nevian , Emily Henderson , University Of Bern , Department Of Physiology , Steering Committe , Artifical Intelligence , Analysis Toolkit , வால்டர் சென்ன் , எமிலி ஹென்டர்சன் , பல்கலைக்கழகம் ஆஃப் பெர்ன் , துறை ஆஃப் உடலியல் , திசைமாற்றி கமிட் , கலை உளவுத்துறை ,