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Use of hs-cTnT Assay Brings Increased Dx of Myocardial Injury, MI


May 4, 2021
But no increases in overall use of resources
The use of high-sensitivity cardiac troponin-T (hs-cTnT) assays significantly increased the number of diagnoses of myocardial injury and myocardial infarction (MI), especially in women and those with type 2 MI; however, apart from angiography, it did not increase the use of overall resources. In patients without increases in cTnT, researchers documented more ED discharges and less cardiac testing.
In the first study of its kind, Olatunde Ola, MD, MPH, of the Mayo Clinic Health System, La Crosse, Wisconsin, and colleagues assessed the transition from a contemporary cardiac troponin T (cTnT) assay that used an overall 99 ....

United States , New Zealand , Christian Mueller , Olatunde Ola , Liz Meszaros , National Center , National Institutes Of Health , Drug Administration , University Of Basel , Mayo Clinic Health System , Translational Sciences , Cardiovascular Research Institute Basel , Journal Of The American College Cardiology , European Society Of Cardiology , American College , Fourth Universal Definition , European Society , North America , Deputy Managing Editor , Mayo Clinic , Advancing Translational Sciences , National Institutes , ஒன்றுபட்டது மாநிலங்களில் , புதியது ஜீலாந்து , கிறிஸ்துவர் முல்லர் , லிஸ் மேஸ்ஜாரொஸ் ,

New VARC-3 Definitions Provide a Road Map for Future Aortic Valve Research


April 23, 2021
The Valve Academic Research Consortium (VARC) has updated their standardized definitions of clinical endpoints for transcatheter and surgical aortic valve clinical trials, including bioprosthetic valve dysfunction and failure, structural complications, conduction disturbances, and repeat hospitalizations, among others. 
Published this week in the
European Heart Journal and the
Journal of the American College of Cardiology, the VARC-3 update was adopted given the “rapid evolution of the field,” including the emergence of new complications, expanding clinical indications, and novel therapy strategies, according to the writing committee.
As aortic valve research moves into younger patients, as well as those with less advanced aortic stenosis, future trials be they head-to-head comparisons of TAVI devices, TAVI versus surgery, or even TAVI or surgery versus medical therapy will need standardized definitions for capturing appropriate endpoints ....

United States , Los Angeles , Sanjay Kaul , Vinod Thourani , Bayer Janssen , Bristol Myers Squibb , Valve Academic Research Consortium , Sinai Medical Center , American College Of Cardiology , Md Piedmont Heart Institute , Drug Administration , Phd Catholic University , Journal Of The American College Cardiology , Society Of Thoracic Surgeons , Md Morristown Medical Center , European Heart Journal , American College , Morristown Medical Center , Allegations Need , Cedars Sinai Medical Center , Piedmont Heart Institute , Thoracic Surgeons , Catholic University , Fourth Universal Definition , ஒன்றுபட்டது மாநிலங்களில் , லாஸ் ஏஞ்சல்ஸ் ,

Differentiating Type 1 and Type 2 MI Still 'Both Art and Science'


April 23, 2021
The hunt continues for a simple lab test that might help clinicians expeditiously sort out which type of MI is afflicting patients who present to the emergency department with chest pain, so as to streamline care. The latest effort, which evaluated 17 novel CV biomarkers, failed to uncover any that offered much in the way of help.
None was significantly better at discriminating between type 1 and type 2 MI when compared with troponins measured using high-sensitivity assays, which themselves have only modest diagnostic value for this purpose, Thomas Nestelberger, MD (Vancouver General Hospital, Canada, and University Hospital Basel, Switzerland), and colleagues report in a study published online April 21, 2021, ahead of print in ....

United States , Thomas Nestelberger , Marc Sabatine , University Hospital Basel , Vancouver General Hospital , Advantageous Predictors , Acute Coronary Syndromes Evaluation , Fourth Universal Definition , ஒன்றுபட்டது மாநிலங்களில் , தாமஸ் நெஸ்டல்பெர்கர் , பல்கலைக்கழகம் மருத்துவமனை பேசல் , வான்கூவர் ஜநரல் மருத்துவமனை , நான்காவது உலகளாவிய வரையறை ,

Myocardial injury in hospitalized patients with COVID-19 infection—Risk factors and outcomes


Myocardial injury in hospitalized patients with COVID-19 infection Risk factors and outcomes
Orly Efros ,
Roles
Conceptualization,
Data curation,
Formal analysis,
Investigation,
Methodology,
Project administration,
Visualization,
Writing – original draft,
Writing – review & editing
Roles
Writing – review & editing
Affiliations
Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel,
Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

Avshalom Leibowitz,
Roles
Writing – review & editing
Affiliations
Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel,
Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

Alexander Fardman,
Roles
Writing – review & editing
Affiliations
Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel,
....

United States , Kaplan Meier , International Classification Of Disease , Ohio State University , Sheba Medical Center , Creative Commons Attribution License , Supporting Information , International Classification , Fourth Universal Definition , Myocardial Infarction , Observational Studies , Log Rank , Covid 19 , Cardiovascular Disease Risk , Blood Pressure , Ace Inhibitor Therapy , ஒன்றுபட்டது மாநிலங்களில் , கபிலன் மையர் , சர்வதேச வகைப்பாடு ஆஃப் நோய் , ஓஹியோ நிலை பல்கலைக்கழகம் , ஷெபா மருத்துவ மையம் , துணை தகவல் , சர்வதேச வகைப்பாடு , நான்காவது உலகளாவிய வரையறை , அவதானிப்பு ஆய்வுகள் , பதிவு ரேங்க் ,