Page 16 - நோவர்த்திச் நிறுவனங்கள் க்கு உயிர் மருத்துவ ஆராய்ச்சி News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Stay updated with breaking news from நோவர்த்திச் நிறுவனங்கள் க்கு உயிர் மருத்துவ ஆராய்ச்சி. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.

Top News In நோவர்த்திச் நிறுவனங்கள் க்கு உயிர் மருத்துவ ஆராய்ச்சி Today - Breaking & Trending Today

Cellular survival after radiation exposure depends on the specific protein behavior


Cellular survival after radiation exposure depends on the specific protein behavior
Exposure to radiation can wreak indiscriminate havoc on cells, tissues, and organs. Curiously, however, some tissues are more vulnerable to radiation damage than others.
Scientists have known these differences involve the protein p53, a well-studied tumor-suppressor protein that initiates a cell s auto-destruct programs. Yet, levels of this sentinel protein are often similar in tissues with vastly different sensitivities to radiation, posing the question: How is p53 involved?
A new study by researchers in the Blavatnik Institute at Harvard Medical School, Massachusetts General Hospital, and the Novartis Institutes for BioMedical Research now sheds light on this mystery. ....

United States , Galit Lahav , Ralph Weissleder , Emily Henderson , Novartis Institutes For Biomedical Research , Blavatnik Institute At Harvard Medical School , Harvard Medical School , Nature Communications On Feb , Blavatnik Institute , Massachusetts General Hospital , Novartis Institutes , Biomedical Research , Nature Communications , Novartis Professor , Systems Biology , Thrall Family Professor , Co Corresponding Author , Harvard Medical , Cell Death , Colon Cancer , Medical School , Radiation Exposure , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , நோவர்த்திச் நிறுவனங்கள் க்கு உயிர் மருத்துவ ஆராய்ச்சி , ஹார்வர்ட் மருத்துவ பள்ளி ,

Radiation Vulnerability


Reporting in
Nature Communications on Feb. 9, they describe how cellular survival after radiation exposure depends on behavior of p53 over time. In vulnerable tissues, p53 levels go up and remain high, leading to cell death. In tissues that tend to survive radiation damage, p53 levels oscillate up and down.
“Dynamics matter. How things change over time matters,” said co-corresponding author Galit Lahav, the Novartis Professor of Systems Biology at HMS. “Our ability to understand biology is limited when we only look at snapshots. By seeing how things evolve temporally, we gain much richer information that can be critical for dissecting diseases and creating new therapies.” ....

United States , Philipp Holzer , Stephane Ferretti , Miles Miller , Ashwini Jambhekar , Mark Prytyskach , Yoshiko Iwamoto , Galit Lahav , Jacob Ornstein , William Forrester , Joerg Kallen , Ralph Weissleder , Cancer Research , Novartis Institutes For Biomedical Research , Blavatnik Institute At Harvard Medical School , National Institutes Of Health , Nature Communications On Feb , Harvard Ludwig Center , Blavatnik Institute , Harvard Medical School , Massachusetts General Hospital , Novartis Institutes , Biomedical Research , Nature Communications , Novartis Professor , Systems Biology ,