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International experts ratchet pressure on China to probe the Covid lab leak theory


Leading infectious disease experts have condemned the World Health Organisation for its failure to properly investigate whether Covid-19 leaked from a laboratory.
In a highly significant move, 18 scientists from the world s top universities, including Cambridge, Harvard and Yale, have demanded further investigations into the origins of the pandemic.
Theories of accidental release from a lab and zoonotic spillover [from animals to humans] both remain viable, they wrote in a letter to the journal Science.
More investigation is needed to determine the origin of the pandemic. Knowing how Covid-19 emerged is critical for informing global strategies to mitigate the risk of future outbreaks. ....

United Kingdom , United States , Donald Trump , Anna Eshoo , Ian Lipkin , David Relman , Alina Chan , Shi Zhengli , Peter Daszak , Ravindra Gupta , David Baltimore , California Institute Of Technology , Broad Institute Of Massachusetts Technology , Ecohealth Alliance , Columbia University , Wuhan Institute Of Virology , World Health Organisation , Wuhan Institute , Ralph Baric , Broad Institute , Massachusetts Institute , California Institute , ஒன்றுபட்டது கிஂக்டம் , ஒன்றுபட்டது மாநிலங்களில் , டொனால்ட் துருப்பு , அண்ணா எஷூ ,

Experts ratchet pressure on China to probe Covid lab leak theory


Experts ratchet pressure on China to probe Covid lab leak theory
Ian Birrell for The Mail on Sunday
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Leading infectious disease experts have condemned the World Health Organisation for its failure to properly investigate whether Covid-19 leaked from a laboratory.
In a highly significant move, 18 scientists from the world s top universities, including Cambridge, Harvard and Yale, have demanded further investigations into the origins of the pandemic.
Theories of accidental release from a lab and zoonotic spillover [from animals to humans] both remain viable, they wrote in a letter to the journal Science.
More investigation is needed to determine the origin of the pandemic. Knowing how Covid-19 emerged is critical for informing global strategies to mitigate the risk of future outbreaks. ....

United Kingdom , United States , Donald Trump , Anna Eshoo , Ian Lipkin , David Relman , Alina Chan , Shi Zhengli , Peter Daszak , Ravindra Gupta , David Baltimore , California Institute Of Technology , Broad Institute Of Massachusetts Technology , Ecohealth Alliance , Columbia University , Wuhan Institute Of Virology , World Health Organisation , Daily Mail Mailonline , Ralph Baric , Wuhan Institute , Broad Institute , Massachusetts Institute , California Institute , ஒன்றுபட்டது கிஂக்டம் , ஒன்றுபட்டது மாநிலங்களில் , டொனால்ட் துருப்பு ,

Using viral load and epidemic dynamics to optimize pooled testing in resource-constrained settings

Frequent and accurate RT-PCR–based testing is essential for preventing and managing SARS-CoV-2 infection; however, active infection surveillance is still often limited by time or resources. Cleary et al. demonstrate that considering population-level viral prevalence and individual viral loads allows for efficiency gains upon pooled testing with minimal loss of sensitivity, both theoretically and as validated in vitro using human swab and sputum samples. Barak et al. show that pooled testing of 133,816 hospital-collected patient nasopharyngeal samples eliminated three quarters of testing reactions with only a minor reduction in sensitivity, demonstrating the efficacy of the approach in the field. Both studies suggest that considered pooling of individual samples before testing could reliably increase SARS-CoV-2 testing throughput.

Virological testing is central to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) containment, but many settings face severe limitations ....

United States , Monte Carlo , Broad Institute Clinical Laboratory Improvement Amendments , Broad Institute Of Massachusetts Technology , Broad Institute Office Of Research , Emergency Use Authorization , Supplementary Materials , Broad Institute Office , Sponsored Programs , Broad Institute , Massachusetts Institute , ஒன்றுபட்டது மாநிலங்களில் , மான்டே கார்லோ , பரந்த நிறுவனம் ஆஃப் மாசசூசெட்ஸ் தொழில்நுட்பம் , அவசரம் பயன்பாடு அங்கீகாரம் , துணை பொருட்கள் , ஆதரவளிக்கப்பட்ட ப்ரோக்ர்யாம்ஸ் , பரந்த நிறுவனம் , மாசசூசெட்ஸ் நிறுவனம் ,

'Massively Parallel' Gene Screening Tool Can Accelerate Research for Nearly Any Disease


Massively Parallel Gene Screening Tool Can Accelerate Research for Nearly Any Disease
Transformative discovery led by experts at Cincinnati Children s began with the deepest dive ever in lupus research but led to an innovation that could boost studies of heart disease, diabetes, asthma and more
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CINCINNATI, March 12, 2021 /PRNewswire/ Ever since the discovery of DNA, scientists have raced to understand which tiny variations among the 3 billion base pairs within the human genome are responsible for causing disease.
While many are familiar with single-gene diseases such as cystic fibrosis or sickle cell anemia, science has lacked the computer and people power to sift through a vast and expanding cloud of genetic data to tease out the patterns involved in complex conditions such as heart disease or asthma. ....

United States , Ohio Center , Leah Kottyan , Daniel Miller Sreeja , John Harley , Ted Hong , Xiaoming Lu , Emily Miraldi , John Ray , Matthew Weirauch , Centers For Disease , Nature Communications , Cincinnati College , National Institutes Of Health , Ohio Supercomputing Center , Veterans Administration , Department Of Pharmacology , Research Committee , Broad Institute Of Massachusetts Technology , Cincinnati Children Hospital Research Foundation Academic , Cincinnati Children Hospital Medical Center , Cincinnati Children , Autoimmune Genomics , Disease Control , Biomedical Informatics , Daniel Miller ,