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Researchers develop a technique to produce transplantable livers in the laboratory


Researchers develop a technique to produce transplantable livers in the laboratory
April 5, 2021ScienceBlog.com
Researchers at the Human Genome and Stem Cell Research Center (HUG-CELL), hosted by the University of São Paulo’s Institute of Biosciences (IB-USP) in Brazil, have developed a technique to reconstruct and produce livers in the laboratory.
The proof-of-concept study was conducted with rat livers. In the next stage of their research, the scientists will adapt the technique for the production of human livers in order in future to increase the supply of these organs for transplantation.
The study was supported by FAPESP and is reported in an article published in  ....

Mayana Zatz , Dissemination Centers Ridcs , Paulo Research Foundation , Stem Cell Research Center , Research Partnership For Technological Innovation Program , Paulo Institute Of Biosciences , Human Genome , Materials Science , Luiz Carlos De Caires J , Dissemination Centers , Research Partnership , Technological Innovation Program , பாலொ ஆராய்ச்சி அடித்தளம் , தண்டு செல் ஆராய்ச்சி மையம் , ஆராய்ச்சி கூட்டு க்கு தொழில்நுட்ப கண்டுபிடிப்பு ப்ரோக்ர்யாம் , பாலொ நிறுவனம் ஆஃப் உயிர் அறிவியல் , மனிதன் மரபணு , பொருட்கள் அறிவியல் , லூயிஸ் கார்லோஸ் டி சைரஸ் ஜு , பரப்புதல் மையங்கள் , ஆராய்ச்சி கூட்டு , தொழில்நுட்ப கண்டுபிடிப்பு ப்ரோக்ர்யாம் ,

Researchers confirm new drug development route for treating multiple sclerosis, asthma


Researchers confirm new drug development route for treating multiple sclerosis, asthma
Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma.
The venomous toadfish Thalassophryne nattereri contains a peptide (TnP) with anti-inflammatory and anti-allergic potential. Confirmation of this potential has now come via the zebrafish Danio rerio, a popular aquarium species native to South Asia that shares 70% of its genome with humans and is widely used as a model for in vivo trials in drug development.
The researchers tested TnP in D. rerio to measure its toxicity. In a little over a year, their research showed that the peptide is safe. It did not cause cardiac dysfunction or neurological problems in the toxicity tests they performed. ....

Lopes Ferreira , Emily Henderson , Dissemination Centers Ridcs , Brazilian Multiple Sclerosis Association , Paulo Research Foundation , Butantan Institute Special Laboratory For Applied Toxinology , Research On Toxins , Zebrafish Network , South Asia , Butantan Institute , Special Laboratory , Applied Toxinology , Immune Response , Cell Signaling , Dissemination Centers , Toxicology Reports , Carla Lima , Zebrafish Platform , Multiple Sclerosis , Animal Model , Anti Inflammatory , In Vivo , லோப்ஸ் ஃபெரீரா , எமிலி ஹென்டர்சன் , பிரேசிலியன் பல ஸ்க்லரோசிஸ் சங்கம் , பாலொ ஆராய்ச்சி அடித்தளம் ,