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Researchers confirm new drug development route for treating multiple sclerosis, asthma


Researchers confirm new drug development route for treating multiple sclerosis, asthma
Brazilian researchers who study a native venomous fish have confirmed a route to drug development for the treatment of chronic inflammatory diseases such as multiple sclerosis and asthma.
The venomous toadfish Thalassophryne nattereri contains a peptide (TnP) with anti-inflammatory and anti-allergic potential. Confirmation of this potential has now come via the zebrafish Danio rerio, a popular aquarium species native to South Asia that shares 70% of its genome with humans and is widely used as a model for in vivo trials in drug development.
The researchers tested TnP in D. rerio to measure its toxicity. In a little over a year, their research showed that the peptide is safe. It did not cause cardiac dysfunction or neurological problems in the toxicity tests they performed. ....

Lopes Ferreira , Emily Henderson , Dissemination Centers Ridcs , Brazilian Multiple Sclerosis Association , Paulo Research Foundation , Butantan Institute Special Laboratory For Applied Toxinology , Research On Toxins , Zebrafish Network , South Asia , Butantan Institute , Special Laboratory , Applied Toxinology , Immune Response , Cell Signaling , Dissemination Centers , Toxicology Reports , Carla Lima , Zebrafish Platform , Multiple Sclerosis , Animal Model , Anti Inflammatory , In Vivo , லோப்ஸ் ஃபெரீரா , எமிலி ஹென்டர்சன் , பிரேசிலியன் பல ஸ்க்லரோசிஸ் சங்கம் , பாலொ ஆராய்ச்சி அடித்தளம் ,