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Coordinative bonding to carbon more nuanced than first thought

By Kirsten Hall2021-03-03T14:22:00+00:00
Research by an international group of scientists provides evidence of covalent, dative and ionic character in one bond. Somewhat unifying a long-running bonding debate on the nature of bonding in a class of molecules called carbones, previously described as purely dative, the work suggests bonding in carbones sits somewhere between electron sharing bonds and dative bonds. The researchers say this provides a new distinction between coordinative bonding to carbon in the molecules studied and the more traditional coordination chemistry of transition metals and their ligands, which form purely dative bonds.
Most will be familiar with carbon using its four valence electrons to form covalent bonds in its ubiquitous tetravalent form. Carbenes (CR ....

Remco Havenith , Gernot Frenking , Michelle Francl , Bryn Mawr College , University Of Groningen , University Marburg , Philipps University Marburg , Bryn Mawr , ப்ரைன் மாயர் கல்லூரி , பல்கலைக்கழகம் ஆஃப் க்ராநிகந் , பல்கலைக்கழகம் மார்பர்க் , ப்ரைன் மாயர் ,

New study suggests better approach in search for COVID-19 drugs

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Research from the University of Kent, Goethe-University in Frankfurt am Main, and the Philipps-University in Marburg has provided crucial insights into the biological composition of SARS-CoV-2, the cause of COVID-19, revealing vital clues for the discovery of antiviral drugs.
Researchers compared SARS-CoV-2 and the closely related virus SARS-CoV, the cause of the 2002/03 SARS outbreak. Despite being 80% biologically identical, the viruses differ in crucial properties. SARS-CoV-2 is more contagious and less deadly, with a fatality rate of 2% compared to SARS-CoV s 10%. Moreover, SARS-CoV-2 can be spread by asymptomatic individuals, whereas SARS-CoV was only transmitted by those who were already ill.
Most functions in cells are carried out by proteins; large molecules made up of amino acids. The amino acid sequence determines the function of a protein. Viruses encode proteins that reprogramme infected cells to produce more viruses. Despite the proteins of SARS-C ....

United Kingdom , France General , Bruxelles Capitale , Sam Wood , Martin Michaelis , Jake Mcgreig , Marek Widera , Sandra Ciesek , Jindrich Cinatl , Stuart Masterson , Denisa Bojkova , University In Marburg , Canterbury Christ Church University , University In Frankfurt Am Main , Medway Medical School , University Of Kent , University Of Kent On Twitter , University Of Kent Press Office , University Frankfurt , Health Education England , Research Assessment Framework , University Marburg , Molecular Medicine , Katie May Mclaughlin , Mark Wass , Philipps University Marburg ,