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Mayo study differentiates what blood-based proteins indicate about brain cell loss


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Mayo study differentiates what blood-based proteins indicate about brain cell loss
Two proteins that can be measured in the blood – plasma total tau and neurofilament light – are associated with brain cell loss that causes memory and thinking problems. Neurofilament light was more strongly related to worse cognition and neurodegeneration, compared to total tau, according to a preliminary Mayo Clinic study that will be presented in the Emerging Science program at the 2021 virtual American Academy of Neurology Annual Meeting.
Brain cell loss, or neurodegeneration, is a common characteristic of many disorders, including Alzheimer’s disease, vascular dementia and Lewy body dementia. However, the causes and location of neurodegeneration in the brain vary depending on the disease. ....

United States , Jeremy Syrjanen , Prashanthi Vemuri , Micheller Campbell , Alicia Algeciras Schimnich , Ronald Petersen , Michelle Mielke , Mary Machulda , Clifford Jack Jr , Jonathan Graff Radford , David Knopman , Alzheimer Disease Neuroimaging Initiative , American Academy Of Neurology Annual Meeting , National Institutes Of Health , National Institute On , Mayo Clinic , Emerging Science , American Academy , Neurology Annual , Mayo Clinic Study , Disease Neuroimaging Initiative , Jordan Marks , National Institutes , National Institute , Rochester Epidemiology , Public Release ,