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Giving chemotherapy in the morning can extend survival of glioblastoma patients

Giving chemotherapy in the morning can extend survival of glioblastoma patients
An aggressive type of brain cancer, glioblastoma has no cure. Patients survive an average of 15 months after diagnosis, with fewer than 10% of patients surviving longer than five years. While researchers are investigating potential new therapies via ongoing clinical trials, a new study from Washington University in St. Louis suggests that a minor adjustment to the current standard treatment -; giving chemotherapy in the morning rather than the evening -; could add a few months to patients survival.
The study appears online in the journal Neuro-Oncology Advances.
Average overall survival for all patients in the study was about 15 months after diagnosis. Those receiving the chemotherapy drug temozolomide in the morning had an average overall survival of about 17 months post diagnosis, compared with an average overall survival of about 13½ months for those taking the drug in the evening, a s ....

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Chemo for glioblastoma may work better in morning than evening | The Source | Washington University in St. Louis

Chemo for glioblastoma may work better in morning than evening | The Source | Washington University in St. Louis
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Obituary: Luis Glaser, former head of biological chemistry department, 88 – Washington University School of Medicine in St. Louis

Glaser
Luis Glaser, PhD, a beloved mentor and former head of the then-Department of Biological Chemistry at Washington University School of Medicine in St. Louis, died Dec. 23, 2020, in Miami after a long illness. He was 88.
Also a director of the university’s Division of Biology & Biomedical Sciences, Glaser spent the latter years of his career, from 1986 to 2005, as executive vice president and provost at the University of Miami.
At Washington University, where he earned his PhD in biochemistry, Glaser studied in the laboratory of Nobel laureates Carl and Gerty Cori. He joined the faculty as an instructor in 1956 and rose to head of the biological chemistry department, precursor to the Department of Biochemistry and Molecular Biophysics; he held that position from 1975 to 1986. He also became director of the Division of Biology & Biomedical Sciences, in 1980. He retired from Washington University in 1986 but remained affiliated with the School of Medicine as an adj ....

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