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Applied DNA Sciences, Inc.: Applied DNA and Evvivax Initiate Phase I of Clinical Trial to Evaluate LinearDNA COVID-19 Vaccine Candidate for Feline Veterinary Market


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- Vaccine Candidate Previously Demonstrated Antibodies and T-cell Response in Mouse Models
- Clinical Trial to Serve as Initial Validation of LinearDNA Platform in Large Mammals with Potential Advantages in Manufacturing, Storage, and Distribution over Other Vaccines
Applied DNA Sciences, Inc. (NASDAQ: APDN) (the Company ), a leader in Polymerase Chain Reaction (PCR)-based DNA manufacturing, and its program development partner, Evvivax, S.R.L. ( Evvivax ), today announced the initiation of Phase I of a two-phase clinical trial to evaluate a LinearDNA COVID-19 vaccine candidate for the feline veterinary market. The goal of the trial is to evaluate the vaccine candidate as a strategy for the prevention of SARS-CoV-2, the virus that causes COVID-19, in feline companions of humans that may mitigate the animals as a potential reservoir for infections in humans. If successful, the clinical trial will also serve as an important initial validation of LinearDNA, Appl ....

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Applied DNA Achieves Program Milestone in Development of Linear DNA Veterinary COVID-19 Vaccine


Press release content from Business Wire. The AP news staff was not involved in its creation.
Applied DNA Achieves Program Milestone in Development of Linear DNA Veterinary COVID-19 Vaccine
February 2, 2021 GMT
STONY BROOK, N.Y. (BUSINESS WIRE) Feb 2, 2021
Applied DNA Sciences, Inc. (NASDAQ: APDN) (the “Company”), a leader in Polymerase Chain Reaction (PCR)-based DNA manufacturing, today announced that it has qualified a freeze-dried (lyophilized) form of its LinearDNA™ COVID-19 vaccine candidate for its upcoming feline clinical trial. Lyophilization renders the vaccine candidate shelf-stable and convenient to ship globally at room temperature, thereby circumventing a key logistical limitation inherent to all existing nucleic acid-based (human and veterinary) vaccines. Quantities of the lyophilized vaccine candidate were manufactured and shipped packaged in vials to its program development partner, EvviVax, S.R.L. (“EvviVax”) for preclinical potency, ste ....

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