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Testicular, Penile, and Rare GU Malignancies


Testicular, Penile, and Rare GU Malignancies
Interviews with Experts at Conferences
Curated by clinicians: educational forums with videos, abstracts and conference information
Videos
April 27, 2021
The State-of-the-Evidence in Brief Reviews by Experts
May 17, 2021
Penile cancer (PC) is  a rare malignancy with an incidence estimated less than 1/100 000 per year in the Western World
1-3
Historically, demolitive surgical approaches, such as total or partial penile amputation, were the most commonly used. Indeed, demolitive options were deemed to be necessary in order to respect a macroscopic surgical margin of at least 2 cm.
3-4 If the oncological outcomes of these approaches demonstrated to be satisfactory, they significantly affected aesthetic outcomes, as well as sexual and urinary functions. ....

United States , New Zealand , Julien Van Damme , Pilar Laguna , Christopher Jd Wallis , Fallen James , Zachary Klaassen , Philippe Spiess , Darren Feldman , Andrea Necchi , Lucia Nappi , Philippee Spiess , Lyndal Moore , James Lynam , Silke Gillessen , Peter Albers , Alok Tewari , Andreas Hiester , Patricia Bastick , European Association Of Urology , European Multidisciplinary Congress On Urological Cancers , Moffitt Cancer Center , Global Society Of Rare Genitourinary Tumors , Cancer Trials Group , International Germ Cell Cancer Collaborative Group , Virtual Annual Congress ,

ANZUP Mini ASM 2020: ANZUP Trial Update - The ENZAMET Trial


ANZUP Mini ASM 2020: ANZUP Trial Update - The ENZAMET Trial
(UroToday.com) The 2020 Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP) Mini Annual Scientific Meeting (ASM) featured a session on ANZUP trial updates, including an update of the critical Phase III ENZAMET trial provided by Drs. Ian Davis, Arun Azad, and Lisa Horvath.
Dr. Davis started by recapping the 2019 publication of ENZAMET.
1 This trial randomly assigned 1,125 metastatic hormone-sensitive prostate cancer (mHSPC) patients from March 31, 2014, to March 24, 2017: 562 in the non-steroidal anti-androgen and 563 in the enzalutamide arm. The trial schema is as follows:
The treatment groups were well balanced for all important baseline factors. In the non-steroidal anti-androgen arm, 44% of patients were planned for early docetaxel, compared to 45% in the enzalutamide arm; 53% of patients in the non-steroidal anti-androgen arm were high volume metastatic burden compared to ....

New Zealand , South Australia , New South Wales , United States , Zachary Klaassen , Ian Davis , Arun Azad , Martin Stockler , Lisa Horvath , Chris Obrien Lifehouse , European Society Of Medical Oncology Annual Congress , Monash University , Eastern Health , Peter Maccallum Cancer Center , Augusta University Medical College Of Georgia , Central Clinical School University Of Sydney , Head Of The Eastern Health Clinical School , Department Of Medical Oncology , Cancer Trials Group , Georgia Cancer Center , Translational Research Committee , New Zealand Urogenital , Mini Annual Scientific Meeting , Medical Oncology Annual Congress , Eastern Health Clinical School , Associate Professor ,

GSRGT 2020: Management of Chemotherapy-Resistant Germ Cell Tumors in 2020


GSRGT 2020: Management of Chemotherapy-Resistant Germ Cell Tumors in 2020
(Urotoday.com) To kick-off a series of lectures discussing testicular cancer at the inaugural meeting of the Global Society of Rare Genitourinary Tumors (GSRGT) 2020 virtual summit, Dr. Andrea Necchi provided the keynote lecture discussing the management of chemotherapy-resistant germ cell tumors. Dr. Necchi started by highlighting the global incidence and mortality of germ-cell tumors:
As follows is an overview of first- and subsequent salvage treatment options:
10-20% of patients will progress/relapse after first-line therapy
A proportion varying from 25% to 60-70% of patients with will be cured by second-line treatments
There are very few randomized trials to guide treatment decisions ....

United States , New Zealand , Zachary Klaassen , Andrea Necchi , Indiana University , Augusta University Medical College Of Georgia , Global Society Of Rare Genitourinary Tumors , Scientific Institute , Cancer Trials Group , Salute San Raffaele University , Georgia Cancer Center , Global Society , Rare Genitourinary Tumors , New Zealand Urogenital , Associate Professor , Vita Salute San Raffaele University , Genitourinary Medical Oncology , Raffaele Hospital , Assistant Professor , Medical College , Rare Genitourinary Tumors Virtual Summit , ஒன்றுபட்டது மாநிலங்களில் , புதியது ஜீலாந்து , சக்கரி க்லாஸ்சேங் , ஆண்ட்ரியா னேக்சி , இந்தியானா பல்கலைக்கழகம் ,