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To learn about gut microbiomes, experts look at ancient feces from dry caves


Researchers want to know what the gut microbiomes were like in humans prior to industrialization.
They examined ancient DNA from ancient dried feces found at a paleontology site.
The gut microbiome is an essential part of the human body’s digestive and immune systems. With modern diets, the species makeup and diversity of the gut microbiome has changed and adapted. Researchers who are hoping to understand what the gut microbiome was like prior to industrialization don’t have many existing populations to study that would be reliably similar. So one group of researchers turned to ancient ruins to find their answers. ....

United States , Aleksandar Kostic , Professor Of Microbiology At Harvard Medical School , Joslin Assistant Investigator , Assistant Professor , Harvard Medical School , Add Changing America , Native American Indigenous , ஒன்றுபட்டது மாநிலங்களில் , உதவியாளர் ப்ரொஃபெஸர் , ஹார்வர்ட் மருத்துவ பள்ளி , பூர்வீகம் அமெரிக்கன் உள்நாட்டு ,

Scientists find dramatic differences between ancient gut microbiomes and modern microbes


Scientists find dramatic differences between ancient gut microbiomes and modern microbes
Scientists are rapidly gathering evidence that variants of gut microbiomes, the collections of bacteria and other microbes in our digestive systems, may play harmful roles in diabetes and other diseases. Now Joslin Diabetes Center scientists have found dramatic differences between gut microbiomes from ancient North American peoples and modern microbiomes, offering new evidence on how these microbes may evolve with different diets.
The scientists analyzed microbial DNA found in indigenous human paleofeces (desiccated excrement) from unusually dry caves in Utah and northern Mexico with extremely high levels of genomic sequencing, says Joslin Assistant Investigator Aleksandar Kostic, PhD, senior author of a ....

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Ancient gut microbiomes may offer clues to modern diseases


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BOSTON - (May 12, 2021) - Scientists are rapidly gathering evidence that variants of gut microbiomes, the collections of bacteria and other microbes in our digestive systems, may play harmful roles in diabetes and other diseases. Now Joslin Diabetes Center scientists have found dramatic differences between gut microbiomes from ancient North American peoples and modern microbiomes, offering new evidence on how these microbes may evolve with different diets.
The scientists analyzed microbial DNA found in indigenous human paleofeces (desiccated excrement) from unusually dry caves in Utah and northern Mexico with extremely high levels of genomic sequencing, says Joslin Assistant Investigator Aleksandar Kostic, PhD, senior author of a ....

United States , University Of Montana , Omar Rota Stabelli , Aleksandar Kostic , Francisco Barajas Olmos , Karl Reinhard , Kun Huang , Johanna Pamp , Steven Leblanc , Maxime Borry , Cecilia Contreras Cubas , Philipp Kirstahler , Joslin Zhen Yang , Richard Arnold , Sonia Ballal , Jacob Luber , Harvard Christina Warinner , Braden Tierney , Lorena Orozco , Humberto Garc , Marsha Wibowo , Bering Strait , Julia Russ , Frank Maixner , Samuel Zimmerman , Nicola Segata ,

Findings reveal insights about evolution of gut microbes in response to diet and environment


Harvard Medical School
Over the past several years, scientists have generated intriguing insights suggesting that variations in gut microbiomes-the collections of bacteria and other microbes in our digestive systems-may play harmful roles that precipitate the development of diabetes and other diseases.
By ERIC BENDER, Joslin Diabetes Cente
Now, researchers at Harvard Medical School and Joslin Diabetes Center have found dramatic differences between gut microbiomes from ancient North American peoples and modern microbiomes, offering further clues about how these microbes may have evolved with changing diets.
For the study, the scientists analyzed microbial DNA found in indigenous human paleofeces (desiccated excrement) from unusually dry caves in Utah and northern Mexico. ....

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