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Over a 26-year period, most new dietary ingredient notifications were met with objections from FDA, government data shows.
Since the mid-1990s, FDA has objected to most new dietary ingredient notifications (NDINs) for one reason or another. This past fiscal year was no different.
In FY20, filed 27 objection letters to NDINs and acknowledged 16 notifications without objection, reflecting an acknowledgement rate of 37.2%, FDA data shows.
Steven Tave, director of FDA’s Office of Dietary Supplement Programs, reminded industry during a 2019 public meeting that “an effective NDI notification process represents FDA s only opportunity to evaluate the safety of a new dietary ingredient before it becomes available to consumers.” ....

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