Study opens up new opportunities for controlling tuberculosis
Boosting the body s own disease-fighting immune pathway could provide answers in the desperate search for new treatments for tuberculosis.
Tuberculosis still represents an enormous global disease burden and is one of the top 10 causes of death worldwide.
Led by WEHI s Dr Michael Stutz and Professor Marc Pellegrini and published in
Immunity, the study uncovered how cells infected with tuberculosis bacteria can die, and that using new medicines to enhance particular forms of cell death decreased the severity of the disease in a preclinical model.
At a glance
Researchers were able to demonstrate that cells infected with tuberculosis bacteria have functional apoptosis cell death pathways, and showed their importance in combatting severe disease.
Progress towards new treatments for tuberculosis
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