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The E484K mutation - a 'backdoor' to undoing vaccine efforts - Mar 10 2021 - Professor Martin Michaelis and Dr Mark Wass - Life Science News Articles


Mar 11 2021 Read 1487 Times
Author: Professor Martin Michaelis and Dr Mark Wass on behalf
of University of Kent
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As we are seeing many novel Covid-19 variants around the world, Professor Martin Michaelis and Dr Mark Wass of University of Kent’s School of Biosciences explain why this may be happening and what these new variants may mean:
‘After almost a year, in which SARS-CoV-2, the coronavirus that causes COVID-19, has not seemed to change its properties, troubling new variants of the virus seem to have only emerged in the last few weeks.
‘Although viruses like SARS-CoV-2 have high mutation rates, they may not change their features until there is a substantial selection pressure that favours new variants. One such selection pressure is caused by an increasing level of immunity in a population. Hence, it is no surprise that novel variants are found in places with high levels of COVID-19 spread or COVID-19 v ....

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New algorithm will prevent misidentification of cancer cells


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Researchers from the University of Kent have developed a computer algorithm that can identify differences in cancer cell lines based on microscopic images, a unique development towards ending misidentification of cells in laboratories.
Cancer cell lines are cells isolated and grown as cell cultures in laboratories for study and developing anti-cancer drugs. However, many cell lines are misidentified after being swapped or contaminated with others, meaning many researchers may work with incorrect cells.
This has been a persistent problem since work with cancer cell lines began. Short tandem repeat (STR) analysis is commonly used to identify cancer cell lines, but is expensive and time-consuming. Moreover, STR cannot discriminate between cells from the same person or animal. ....

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