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Griffith University: Griffith University researchers develop vaccine for human babesiosis

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In a world-first, Griffith University researchers have developed a new vaccine in pre-clinical studies to treat human babesiosis, a tick-transmitted disease closely related to malaria.
Lead researcher Professor Michael Good AO, said the research team including PhD candidate Hanan Al-Nazal and researcher Dr Danielle Stanisic, developed a whole parasite Babesia vaccine that acts as a universal vaccine, inducing immunity against different human Babesia species.
“Babesiosis affects the red blood cells similar to malaria in humans and animals and presents as a flu-like illness and anaemia. People most at risk of severe disease are the elderly, the immunosuppressed and those without spleens. It also affects those who need blood transfusions,’’ Professor Good said. ....

Hanan Al Nazal , Danielle Stanisic , Griffith University , Institute For Glycomics Professor Mark Von Itzstein , Professor Michael Good , Professor Good , Glycomics Professor Mark , கிரிஃபித் பல்கலைக்கழகம் , ப்ரொஃபெஸர் மைக்கேல் நல்ல , ப்ரொஃபெஸர் நல்ல ,

Researchers develop vaccine for human babesiosis

Babesia parasites inside red blood cell.
Griffith University researchers have developed a new vaccine in pre-clinical studies to treat human babesiosis, a tick-transmitted disease closely related to malaria.
Lead researcher Professor Michael Good AO, said the research team including PhD candidate Hanan Al-Nazal and researcher Dr Danielle Stanisic, developed a whole parasite Babesia vaccine that acts as a universal vaccine, inducing immunity against different human Babesia species.
“Babesiosis affects the red blood cells similar to malaria in humans and animals and presents as a flu-like illness and anaemia. People most at risk of severe disease are the elderly, the immunosuppressed and those without spleens. It also affects those who need blood transfusions,” Professor Good said. ....

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Australia: Researchers develop vaccine in pre-clinical studies for human babesiosis

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Lead researcher Professor Michael Good AO, said the research team including PhD candidate Hanan Al-Nazal and researcher Dr Danielle Stanisic, developed a whole parasite
Babesia vaccine that acts as a universal vaccine, inducing immunity against different human
Babesia species.
“Babesiosis affects the red blood cells similar to malaria in humans and animals and presents as a flu-like illness and anaemia. People most at risk of severe disease are the elderly, the immunosuppressed and those without spleens. It also affects those who need blood transfusions,’’ Professor Good said.
“In pre-clinical studies we have shown this vaccine can kill the parasite and induce a protective immune response. The immune response is tied to two crucial aspects of the immune system – T Cells and macrophages (which clear bacteria and other germs).” ....

Hanan Al Nazal , Danielle Stanisic , Griffith University , Professor Michael Good , Professor Good , கிரிஃபித் பல்கலைக்கழகம் , ப்ரொஃபெஸர் மைக்கேல் நல்ல , ப்ரொஃபெஸர் நல்ல ,

New research may be key to making safe, durable COVID-19 vaccines

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New research may be key to making safe, durable COVID-19 vaccines
Representative microscopy image of SARS-CoV-2 infected cells stained with antibodies in convalescent plasma. Image credit: Dr Michael Joyce, University of Alberta.
Using convalescent plasma, Griffith University researchers have identified how it may be possible to make a future vaccine that will provide protection against all major strains of COVID-19.
Vaccines work by inducing antibodies that block the interaction between the receptor binding domain (RBD) of SARS-CoV-2’s Spike protein and its receptor, angiotensin converting enzyme 2 (ACE2), which is present on human lungs.
To understand how antibodies block infection, the researchers from the Institute for Glycomics, with colleagues from the Gold Coast University Hospital, the University of Queensland, the University of Alberta, Canada, and Olymvax Pharmaceuticals, Chengdu, identified the minimal sequences of the RBD recognised by ....

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Researchers tout promising vaccine for deadly bacterial infection

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As vaccines against COVID-19 are rolled out around the world, a group of researchers has been working on a groundbreaking vaccine for a different deadly disease.
Streptococcus A (strep A) is a bacterial infection that kills more than 500,000 people every year.
Streptococcus bacteria kill half a million people worldwide every year.
There is no vaccine to protect against strep A, but researchers from the Griffith University Institute for Glycomics believe they have developed one.
Lead researcher Manisha Pandey said the team developed a vaccine by combining two proteins from the bacteria with an adjuvant, a substance that stimulates an immune response from the body. ....

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