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CUHK study brings new direction for treating neurological diseases

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IMAGE: Under normal situation (image on the left), the closely packed choroid plexus restrains molecules in the blood stream from entering the CSF freely; the loss of SOX9 function (image on.
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Credit: CUHK
The finding, recently published in the prestigious scientific journal
Proceedings of the National Academy of Sciences of the United States of America (PNAS), has provided the scientific community a novel understanding to the molecular regulatory mechanisms behind the function of the blood-CSF barrier and lays the groundwork for developing novel therapeutic strategies for preventing and treating neurodevelopmental disorders.
Dysfunction of blood-cerebrospinal fluid barrier is common in various neurological diseases ....

United States , Hong Kong , Jiang Liwen , School Of Life Sciences , Collaborative Research Fund , Key Laboratory Of Agrobiotechnology , School Of Life Science , Research Fund , Centre For Cell , National Academy , Associate Professor , Life Science , Professor Jiang Liwen , Professor Ngai Sai Ming , Professor Hui Ho Lam Jerome , Life Sciences , General Research Fund , Hong Kong Research Grants Council , Developmental Biology , State Key Laboratory , Medicine Health , ஒன்றுபட்டது மாநிலங்களில் , ஹாங் காங் , பள்ளி ஆஃப் வாழ்க்கை அறிவியல் , கூட்டு ஆராய்ச்சி நிதி , ஆராய்ச்சி நிதி ,

CUHK Uncovers Molecular Mechanism Regulating Blood-cerebrospinal Fluid Barrier Function in Developing Brain New Direction for Treating Neurological Diseases

CUHK Uncovers Molecular Mechanism Regulating Blood-cerebrospinal Fluid Barrier Function in Developing Brain New Direction for Treating Neurological Diseases
A research team from the School of Life Sciences at The Chinese University of Hong Kong (CUHK) has recently discovered that SOX9 protein is an essential regulatory factor of choroid plexus function that ensures the correct composition of cerebrospinal fluid (CSF). The finding, recently published in the prestigious scientific journal Proceedings of the National Academy of Sciences of the United States of America (PNAS), has provided the scientific community a novel understanding to the molecular regulatory mechanisms behind the function of the blood-CSF barrier and lays the groundwork for developing novel therapeutic strategies for preventing and treating neurodevelopmental disorders. ....

Hong Kong , Jiang Liwen , School Of Life Sciences , Collaborative Research Fund , Key Laboratory Of Agrobiotechnology , School Of Life Science , Research Fund , Centre For Cell , Associate Professor , Life Science , Professor Jiang Liwen , Professor Ngai Sai Ming , Professor Hui Ho Lam Jerome , Life Sciences , General Research Fund , Hong Kong Research Grants Council , Developmental Biology , State Key Laboratory , ஹாங் காங் , பள்ளி ஆஃப் வாழ்க்கை அறிவியல் , கூட்டு ஆராய்ச்சி நிதி , ஆராய்ச்சி நிதி , மையம் க்கு செல் , இணை ப்ரொஃபெஸர் , வாழ்க்கை அறிவியல் , ப்ரொஃபெஸர் ஹுய் ஹோ லாம் ஜெரோம் ,