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Study describes cardiovascular effects of grape seed extract


Study describes cardiovascular effects of grape seed extract
Supplementation with grape seed extract can significantly modulated blood pressure, especially in men, and may also help to reduce the perception of stress, according to a new RCT.
Enovita, Indena s standardised grape seed extract (GSEe) from Vitis vinifera L. seeds, has previously been found​ to produce beneficial cardiovascular effects.
The current study aimed to discover the mechanism of action behind this benefit with an in vitro experiment using human umbilical vein endothelial cells (HUVEC). 
The results suggested GSEe lead to a significant reduction of the adhesion molecules linked to inflammatory processes in endothelial cells (sICAM, sVCAM, and endothelin-1).  ....

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Depression Supplement FDA Warnings


Monday, February 22, 2021
FDA will evaluate claims and other information on a dietary supplement’s website to establish the product’s “intended use.”  In general, a dietary supplement is allowed to make claims about having an effect on the “structure” or a “function” of the human body.  If FDA finds that the product is intended for use in the cure, mitigation, treatment, or prevention of disease, it will be deemed a “drug” under section 201(g)(1)(B) of the Federal Food, Drug, and Cosmetic Act (“FD&C Act”).  FDA routinely takes enforcement action against such unapproved new drugs.
In a February 18, 2021 Constituent Update, FDA announced that it had issued warning letters to 10 companies for illegally selling dietary supplements, containing a variety of ingredients, that all claim on their websites, as well as their Amazon product pages in some cases, to cure, treat, mitigate, or prevent depression and other mental health disorders as ....

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