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Researchers make new drug compound for stopping malaria


Researchers make new drug compound for stopping malaria
ANI |
Updated: May 15, 2021 16:53 IST
London [UK], May 15 (ANI): During a recent study, researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis designed a drug-like compound that effectively blocks a critical step in the malaria parasite life cycle. They are working to develop this compound into a potential first-of-its-kind malaria treatment.
While drugs and mosquito control have reduced levels of malaria over recent decades, the parasite still kills over 400,000 people every year, infecting many more. Worryingly, it has now developed resistance to many existing antimalarial drugs, meaning new treatments that work in different ways are urgently needed. ....

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Scientists design new drug compound to stop malaria in its tracks


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Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.
While drugs and mosquito control have reduced levels of malaria over recent decades, the parasite still kills over 400,000 people every year, infecting many more. Worryingly, it has now developed resistance to many existing antimalarial drugs, meaning new treatments that work in different ways are urgently needed.
In their research, published in
PNAS, the scientists developed a set of compounds designed to stop the parasite being able to burst out of red blood cells, a process vital to its replication and life cycle. They found one compound in particular was highly effective in human cell tests. ....

United Kingdom , City Of , Chrislaine Withers Martinez , Mike Blackman , University College London , King College London , Imperial College London , Cancer Research United Kingdom , Malaria Biochemistry Laboratory , Latvian Institute Of Organic Synthesis , Research Council , Francis Crick Institute , Latvian Institute , Organic Synthesis , Medical Research Council , Medicine Health , Disease In The Developing World , ஒன்றுபட்டது கிஂக்டம் , நகரம் ஆஃப் , மைக் கருப்பு மனிதன் , பல்கலைக்கழகம் கல்லூரி லண்டன் , கிங் கல்லூரி லண்டன் , ஏகாதிபத்தியம் கல்லூரி லண்டன் , புற்றுநோய் ஆராய்ச்சி ஒன்றுபட்டது கிஂக்டம் , மலேரியா உயிர் வேதியியல் ஆய்வகம் , லாட்வியன் நிறுவனம் ஆஃப் ஆர்க்யாநிக் தொகுப்பு ,

New drug-like compound could effectively block a critical step in malaria parasite life cycle


New drug-like compound could effectively block a critical step in malaria parasite life cycle
Researchers at the Francis Crick Institute and the Latvian Institute of Organic Synthesis have designed a drug-like compound which effectively blocks a critical step in the malaria parasite life cycle and are working to develop this compound into a potential first of its kind malaria treatment.
While drugs and mosquito control have reduced levels of malaria over recent decades, the parasite still kills over 400,000 people every year, infecting many more. Worryingly, it has now developed resistance to many existing antimalarial drugs, meaning new treatments that work in different ways are urgently needed. ....

Chrislaine Withers Martinez , Mike Blackman , Emily Henderson , Malaria Biochemistry Laboratory , Francis Crick Institute , Latvian Institute Of Organic Synthesis , Latvian Institute , Organic Synthesis , Francis Crick , மைக் கருப்பு மனிதன் , எமிலி ஹென்டர்சன் , மலேரியா உயிர் வேதியியல் ஆய்வகம் , பிரான்சிஸ் கிரிக் நிறுவனம் , லாட்வியன் நிறுவனம் ஆஃப் ஆர்க்யாநிக் தொகுப்பு , லாட்வியன் நிறுவனம் , ஆர்க்யாநிக் தொகுப்பு , பிரான்சிஸ் கிரிக் ,