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Credit: Thor Balkhed/Linköping University
Special immune cells found in the brain, microglia, play a key role in the processes that make you feel uneasy and depressed in correlation with inflammation. This is the conclusion of a study using mice carried out by researchers at Linköping University, Sweden. The results have been published in the scientific journal
Immunity, and suggest that microglial cells contribute to the negative mood experienced during several neurological diseases, and maybe also depression.
David Engblom s research group at Linköping University has spent many years looking at why inflammation in the body, such as a common cold or influenza, causes us to feel poorly and despondent, and why we feel like retiring into our shell. The activity of the immune system influences nerve cells in some way. However, normal cells of the immune system are not able to get into the brain: it is sensitive and must be protected. Instead, the brain has its own spe ....

Juan Hidalgo , Michael Fritz , Julia Levinsson , David Engblom , Maarit Jaarola , Johan Jakobsson , Marco Pignatelli , Carla Canal , Antonello Bonci , Hugoa Tejeda , Annam Klawonn , Silvia Castany , Markus Heilig , Department Of Biomedical , Swedish Research Council , Alice Wallenberg Foundation , Swedish Brain Foundation , Lars Hierta Memorial Foundation , Clinical Sciences , Fredrik Simil , ஜுவான் ஹிட்யால்கோ , மைக்கேல் ஃப்ரிட்ஸ் , மார்கோ பிக்நேடெலி , கார்லா கால்வாய் , மார்கஸ் ஹீலிக் , துறை ஆஃப் உயிர் மருத்துவ ,