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Synthetic Biologics Announces First Patient Dosed in Phase 1b/2a Clinical Trial of SYN-004 (ribaxamase) in Allogeneic Hematopoietic Cell Transplant Recipients


Published: Apr 14, 2021
ROCKVILLE, Md., April 14, 2021 /PRNewswire/
Synthetic Biologics, Inc. (NYSE American: SYN), a diversified clinical-stage company leveraging the microbiome to develop therapeutics designed to prevent and treat gastrointestinal (GI) diseases in areas of high unmet need, today announced enrollment has commenced and the first patient has been dosed in its Phase 1b/2a clinical trial of SYN-004 (ribaxamase) in allogeneic hematopoietic cell transplant (HCT) recipients for the prevention of acute graft-versus-host-disease (aGVHD). Broad spectrum intravenous (IV) beta-lactam antibiotics used to treat infection following conditioning chemotherapy for allogeneic HCT patients is a necessary and oftentimes lifesaving intervention. However, antibiotic-mediated damage of the gut microbiome in this patient population has been strongly associated with adverse outcomes including ....

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HIBS: 3 Stocks to Own as Regional Banks Rebound


3 Stocks to Own as Regional Banks Rebound
HIBS – Regional bank stocks Hingham Institution for Savings (HIFS), Webster Financial (WBS), and German American Bancorp (GABC) don’t get much attention, but they should. Here’s why.
Jan 7, 2021
In just the first few days of trading in 2021, regional bank stocks are soaring.  The SPDR S&P Regional Banking ETF (KRE) is up more than 12%, while the  S&P 500 is trading just 1.29% higher.  
The banking industry saw more than its fair share of challenges in 2020, ranging from the closure of branches due to the coronavirus pandemic, to the increased competition from non-bank fintechs. The Deloitte Center for Financial Services is estimating that the U.S. banking industry may have to provision for a total of $318 billion in net loan losses from 2020 to 2022, which would represent 3.2% of loans. ....

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