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Uncovering the Anti-Myeloma Resistance Files


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Multiple myeloma (a type of blood cancer) patients live much longer today than in the past, thanks to new targeted anti-myeloma drugs, but ultimately most develop resistance to the medications, and in some the disease is resistant to therapy from the start. Weizmann Institute of Science researchers, in collaboration with physicians from 
Tel Aviv Sourasky Medical Center (TASMC), have made use of extremely sensitive genomic technology to reveal genetic pathways that characterize some of the more resistant cases of multiple myeloma. 
Nature Medicine, may lead to a more informed, personalized treatment for these patients, and it paves the way to using this new technology for discovering additional disease targets in other cancers. ....

Mouna Ballan , Tamar Tadmor , Yaelc Cohen , Gadi Moshe , Oren Pasvolsky , Chezi Ganzel , Meirav Laiba , Chamutal Bornstein , Baoguo Li , Eyal David , Jacqui Scheinberg , Ido Amit , Assaf Weiner , Osnat Jarchowcky Dolberg , Efrat Luttwak , Noa Lavi , Mor Zada , Irit Avivi , Olga Shvetz , Chamutal Gur , Evgeni Chubar , Iuliana Vaxman , Ofer Shpilberg , Anatoly Nemets , Anita James Rosen Foundation , Moross Integrated Cancer Center ,

Copying Foreign Genes Helps Bacteria Withstand the Test of Time


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Consider the following dilemma: You turn up for an exam, having no prior knowledge of the subject. You are handed one of two opportunities: You can get your answers either from an expert, but in a completely different language from yours or, alternatively, from someone who has only passable knowledge, but shares your language. Which would you choose?
Bacteria were put to a similar test in the lab of Prof. Yitzhak Pilpel of the Weizmann Institute of Science’s Molecular Genetics Department. He, Dr.OrnaDahan and other members of his lab team asked: When bacteria take on foreign genes, how does this affect their chances of survival, and do the bacteria prefer to take these genes from species that “speak” their language? ....

Mediterranean Sea , Oceans General , Yitzhak Pilpel , Itamar Fran , Emile Mimran , Julia Forchheimercenter , Head Of The Kahn Family Research Center , European Research Council , Sharon Zuckerman Laboratory For Research , Weizmann Institute Of Science Molecular Genetics Department , Weizmann Institute , Molecular Genetics , Shai Slomka De Oliveira , Dead Sea , Says Pilpel , Martin Kimmel Award , Azrieli Institute , Systems Biology , Kahn Family Research Center , Sharon Zuckerman Laboratory , European Research , Ben May Professorial , மத்திய தரைக்கடல் கடல் , பெருங்கடல்கள் ஜநரல் , ஈடமார் ஃப்ர்யாந் , தலை ஆஃப் தி கான் குடும்பம் ஆராய்ச்சி மையம் ,