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New technology offers a faster, easier and more efficient way to study gene function

New technology offers a faster, easier and more efficient way to study gene function
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

Hermana Dierick , Koenjt Venken , Nick Matinyan , Emily Henderson , Marrs Mclean Department Of Biochemistry , Danl Duncan Comprehensive Cancer Center , Johns Hopkins University School Of Medicine , Baylor College Of Medicine , Baylor College , Cell Reportsthe , Johns Hopkins University School , Marrs Mclean Department , Molecular Biology , எமிலி ஹென்டர்சன் , மார்ஸ் மக்லீந் துறை ஆஃப் உயிர் வேதியியல் , ஜான்ஸ் ஹாப்கின்ஸ் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , பேலர் கல்லூரி ஆஃப் மருந்து , பேலர் கல்லூரி , ஜான்ஸ் ஹாப்கின்ஸ் பல்கலைக்கழகம் பள்ளி , மார்ஸ் மக்லீந் துறை , மூலக்கூறு உயிரியல் ,

Enzyme from fungi shows molecules which way to turn

Enzyme from fungi shows molecules which way to turn
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Tong Zhu , United States , Rice University , Yang Gao , Baylor College Of Medicine , Zhiwen Liu , George Phillips , Fanglong Zhao , Boyang Zhao , Xue Sherry Gao , Joseph Ferrara , Biki Bapi Kundu , Bv Venkataram Prasad , Banumathi Sankaran , Nature Communications , Roberta Welch Foundation , Jeff Fitlow Rice University , China Normal University , Marrs Mclean Department Of Biochemistry , Georger Brown School Of Engineering , Baker Institute For Public , Department Of Chemical , National Natural Science Foundation Of China , National Institutes Of Health , Zhiwen Liu Rice University , Natural Sciences ,

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell
Just as people keep their houses clean and clutter under control, a crew of cells in the body is in charge of clearing the waste the body generates, including dying cells. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means eating cells. The housekeepers engulf and ingest the dying cells and break them down to effectively eliminate them.
Phagocytosis is very important for the body s health, said Dr. Zheng Zhou, whose lab at Baylor College of Medicine has been studying phagocytosis for many years and provided key new insights into this essential process. ....

Yoshitaka Furuta , Emily Henderson , Marrs Mclean Department Of Biochemistry , Baylor Development , Baylor College Of Medicine , Therapeutics Graduate Program , Baylor Danl Duncan Comprehensive Cancer Center , Baylor College , Marrs Mclean Department , Molecular Biology , Disease Models , Therapeutics Graduate , Danl Duncan Comprehensive Cancer , எமிலி ஹென்டர்சன் , மார்ஸ் மக்லீந் துறை ஆஃப் உயிர் வேதியியல் , பேலர் வளர்ச்சி , பேலர் கல்லூரி ஆஃப் மருந்து , பேலர் கல்லூரி , மார்ஸ் மக்லீந் துறை , மூலக்கூறு உயிரியல் , நோய் மாதிரிகள் ,

In a cell-eat-cell world calcium ions activate 'eat-me' signal in necrotic cells

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Just as people keep their houses clean and clutter under control, a crew of cells in the body is in charge of clearing the waste the body generates, including dying cells. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means eating cells. The housekeepers engulf and ingest the dying cells and break them down to effectively eliminate them.
Phagocytosis is very important for the body s health, said Dr. Zheng Zhou, whose lab at Baylor College of Medicine has been studying phagocytosis for many years and provided key new insights into this essential process. When this cell-eat-cell process fails, the dying cells will lose their integrity, break down and release their content into the surrounding tissues. Dumping the cell content would cause direct tissue damage and trigger inflammatory and autoimmune responses. If the dying cells are infected by a virus, releasing the cellular content would spread the infection. ....

Yoshitaka Furuta , Omar Pena Ramos , Marrs Mclean Department Of Biochemistry , Baylor Development , Baylor College Of Medicine , Lucia Chiao At Baylor College Of Medicine , Therapeutics Graduate Program , Baylor Danl Duncan Comprehensive Cancer Center , Nihondaihyou Program , Baylor College , Marrs Mclean Department , Molecular Biology , Disease Models , Therapeutics Graduate , Danl Duncan Comprehensive Cancer , Lucia Chiao , Tobitate Ryugaku , மார்ஸ் மக்லீந் துறை ஆஃப் உயிர் வேதியியல் , பேலர் வளர்ச்சி , பேலர் கல்லூரி ஆஃப் மருந்து , பேலர் கல்லூரி , மார்ஸ் மக்லீந் துறை , மூலக்கூறு உயிரியல் , நோய் மாதிரிகள் ,

Targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers

Targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers
Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body s immune response.
A new study published in
Cell shows that endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection. Researchers suggest this mechanism could open new avenues for turning on the immune system in aggressive cancers like TNBC.
We know therapeutics that partially interfere with RNA splicing can have a very strong impact on tumor growth and progression, but the mechanisms of tumor killing are largely unknown. In this study, we discovered that these therapeutics are modulators of anti-tumor immunity, said Dr. Trey Westbrook, corresponding author of the study, execu ....

Jarey Wang , Trey Westbrook , Elizabeth Bowling , Emily Henderson , Therapeutic Innovation Center , Marrs Mclean Department Of Biochemistry , Study Co , Mcnair Scholar In Cancer Research At Baylor , Department Of Molecular , Baylor Medical Scientist Training Program , Researchers At Baylor College Of Medicine , Baylor College , Mcnair Scholar , Cancer Research , Study Co First Author , Baylor Medical Scientist Training , Welch Chair , Marrs Mclean Department , Molecular Biology , Human Genetics , Danl Duncan Comprehensive Cancer Center , Breast Cancer , Immune Response , Triple Negative Breast Cancer , Cell Death , Immune System ,