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Graduate students Musslick and Ristroph named Schmidt Science Fellows

Graduate students Musslick and Ristroph named Schmidt Science Fellows
Liz Fuller-Wright, Office of Communications
June 9, 2021 2:12 p.m.
Eric and Wendy Schmidt announced on June 3 that two Princetonians are among 28 new Schmidt Science Fellows: Sebastian Musslick and Kurt Ristroph, graduate students who anticipate finishing their Ph.D.s within the next year.
The year-long fellowship, a program of Schmidt Futures in partnership with the Rhodes Trust, seeks to develop the next generation of science leaders through interdisciplinary research to solve the world’s most pressing problems.
“The Schmidt Science Fellows are proving that bringing together brilliant people across disciplines is the only way to tackle the problems our world faces this century,” said Wendy Schmidt, co-founder of Schmidt Futures and president of The Schmidt Family Foundation. ....

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Princeton technology could help improve COVID-19 vaccines

Rachel Nuwer for the Office of Engineering Communications
March 16, 2021 10:01 a.m.
A team of Princeton engineers led by Robert Prud homme and Shahram Hejazi have found a way to encapsulate drugs and biological molecules in nanoparticles, allowing for more efficient delivery of vaccines and other medications.
Illustration by Neil Adelantar
A new technology being developed by Princeton University researchers and alumni could offer a more effective and robust delivery method for COVID-19 vaccines.
Compared to current vaccines, the technology, which relies on a new type of nanoparticle, could introduce five times as much of the vaccine’s active ingredient, mRNA, into recipients’ cells. This technology will be a boon for triggering a stronger immune response while also providing a more scalable vaccine production line, according to Robert Prud’homme, a professor of chemical and biological engineering, and Shahram Hejazi, a faculty member at the Keller Cen ....

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Integral Molecular and Optimeos Partner to Deliver Long-acting Therapeutic Antibodies Using Nanoparticle Formulation Technology

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PHILADELPHIA, Jan. 7, 2021 /PRNewswire/ Integral Molecular and Optimeos Life Sciences have partnered to develop antibody therapeutics using long-acting, sustained delivery formulations that will improve patient care and quality of life. The partnership will leverage Integral Molecular s industry-leading platform for antibody discovery and include novel targets in cancer and autoimmune diseases. The therapeutics developed using Optimeos inverse flash nanoprecipitation (iFNP) platform will reduce the frequency of antibody injections for patients.
Frequent IV administration is burdensome for patients and can greatly hinder the widespread adoption of therapeutic antibodies in the clinic, said Benjamin Doranz, PhD, President and CEO of Integral Molecular. Optimeos has solved this problem by encapsulating antibodies in nanoparticles to create long-acting, safe formulations which will improve many biotherapeutics on the market. ....

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