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[Full text] Immunotherapeutics for Ebola virus Disease

Taï Forest ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus (BDBV), and Bombali ebolavirus. Filoviruses are pleomorphic in shape and possess a lipid envelope. The viral genome is a negative-sense single strand RNA which is approximately 19 kb in size. Since the first outbreak in 1976, EBOV has resurfaced a multitude of times in Africa. Initially, it was responsible for causing small, localized outbreaks until 2013, when the large multinational epidemic was recorded causing 28,646 infections and 11,323 fatalities. 2 A second, large outbreak occurred in the North Kivu province of the Democratic Republic of Congo (DRC) in 2018–2020 totaling 3481 cases and 2299 fatalities. 3,4 There has recently been an outbreak in the Equateur province, which was declared over on November 18th, 2020.

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