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Genetic variation associated with COVID-19 outcome

Genetic variation associated with COVID-19 outcome
The severity of outcome from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is widely varied, with most individuals remaining asymptomatic while others experience severe life-threatening pneumonia and multi-organ failure. Host genetics play a role in disease progression and prognosis. A paper recently uploaded to the preprint server
et al. (1
st March 2021) identifies several alleles associated with the gene natriuretic peptide receptor C (NPR3) that may impact disease severity.
How was the study performed?
The group worked with 4,488 high-risk COVID-19 outpatients being over 40 years of age and having at least one other comorbidity such as diabetes or obesity. The group was split into two equal sizes, one of which received a placebo, while the other received 0.5 mg colchicine, an anti-inflammatory, daily for a month. The patients were evaluated for disease symptoms 15 and 30 days into ....

Michael Greenwood , Image Credit , Chromosome 9 , Corona Virus , Coronavirus Disease Covid 19 , Sars Cov 2 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , மைக்கேல் கிரீன்வுட் , படம் கடன் , கொரோனா வைரஸ் , நீரிழிவு நோய் , உடல் பருமன் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Locus Partners With Lytx To Offer Future-Ready Logistics

/PRNewswire/ Locus, a global B2B SaaS company that automates human decisions in the supply chain, today announced a new integration with Lytx®, the leader. ....

United States , Krishna Khandelwal , Frank Schneider , Chief Business Officer , Southeast Asia , North America , Indian Subcontinent , ஒன்றுபட்டது மாநிலங்களில் , கிருஷ்ணா கண்டெழுவாள் , வெளிப்படையான ஶ்நைடர் , தலைமை வணிக அதிகாரி , தென்கிழக்கு ஆசியா , வடக்கு அமெரிக்கா ,

Neanderthal gene can confer protection against severe COVID-19, finds study

Neanderthal gene can confer protection against severe COVID-19, finds study
Some of the genes in the human genome appear to confer a protective effect against severe coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A new paper published online in the journal
PNAS describes genes involved in innate immunity that have undergone variations between different human subgroups.
Infectious disease and genetic changes
Infectious diseases vary in prevalence with environmental conditions, which vary dramatically in different parts of the world. These act as selective factors on gene variants, such as the toll-like receptor gene variants that reduce the susceptibility to some bacterial infections and allergies. ....

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Researchers find CXCR6 gene plays a role in COVID-19 severity

Researchers in the United States have conducted a study demonstrating that a gene called CXCR6 (C-X-C Motif Chemokine Receptor 6) may play an important role in determining the severity of COVID-19. ....

United States , New York , Cornell University , Sally Robertson , C Xc Motif Chemokine Receptor , Texas Health Science Center , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Gene Expression , Intensive Care , ஒன்றுபட்டது மாநிலங்களில் , புதியது யார்க் , கார்னெல் பல்கலைக்கழகம் , சாலி ராபர்ட்சன் , டெக்சாஸ் ஆரோக்கியம் அறிவியல் மையம் , கொரோனா வைரஸ் , கீந் வெளிப்பாடு , தீவிர பராமரிப்பு ,

Blood group associated with cardiovascular events in COVID-19 patients

Blood group associated with cardiovascular events in COVID-19 patients
Among the many complications that have emerged from coronavirus disease 2019 (COVID-19), cardiovascular events have become prominent.
An illuminating new study by scientists at Harvard Medical School, USA, describes the correlation of such conditions with the ABO blood group. The team s findings may help assess the risk of COVID-19 patients for such complications, promoting early diagnosis and underscoring potential needs for preventive and therapeutic care where possible.
Study details
The study took a retrospective observational cohort design. It included over 400 subjects enrolled in the COVID-19 Registry to Assess Frequency, Management, and Outcomes of Arterial and Venous Thromboembolic Complications (CORONA-VTE). ....

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