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UNION therapeutics A/S receives FDA approval for IND of oral next generation PDE4-inhibitor (orismilast) for investigation in plaque psoriasis


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- Orismilast is a next generation oral PDE4-inhibitor with an improved therapeutic window compared to other PDE4-inhibitors
- Oral orismilast (UNI50001) has demonstrated proof of concept in patients living with plaque psoriasis and indicated best-in-class potential
- PDE4-inhibition is a validated pharmacological target published for a broad range of inflammatory indications
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- The improved therapeutic window of orismilast suggests potential for use in a number of inflammatory conditions, which have so far been limited by the typical narrow therapeutic window of PDE4-inhibitors
HELLERUP, Denmark, Jan. 7, 2021 /PRNewswire/ UNION therapeutics A/S (UNION) today announces that the US Food and Drug Administration (FDA) has approved an Investigational New Drug program (IND) for oral orismilast; a next generation PDE4-inhibitor for the treatment of plaque psoriasis in adults. ....

Marie Louise Jersin , Kostenloser Wertpapierhandel , Morten Boesen , Morten Sommer , Kim Domela Kjoeller , Drug Administration , Szpirt Company , Investigational New Drug , Professor Morten , Not So Common Comorbidities , Semin Cutan Med , மார்டந் போஸன் , மார்டந் சோமர் , ப்ரொஃபெஸர் மார்டந் ,

Are yellow teeth embarrassing you? Know its causes and remedies


Updated Dec 25, 2020 | 10:00 IST
Even though dental hygiene often goes unacknowledged, it is essential as it helps various oral diseases at bay.
Are yellow teeth embarrassing you? Know its causes and remedies  |  Photo Credit: iStock Images
Key Highlights
Yellowing of teeth is an common issue.
Here is how you can prevent your teeth from turning yellow.
New Delhi: The phenomenon of the teeth turning yellow is experienced widely. Teeth are considered to be a contributing factor to the aesthetic appeal of a person s face. Furthermore, people find yellow teeth unappealing. The issue of yellow teeth may be due to various reasons. Age and genetics are two major contributing factors to this issue. Apart from that, some other reasons may include chronic dry mouth, smoking, drinking, a diet high in simple carbohydrates and sugar, mouth trauma, side effects of medications, and poor oral hygiene. There are a few ways in which you ....

New Delhi , Photo Credit , Stock Images , Yellow Teeth , Yellow Teeth Causes , Yellow Teeth Remedies , புதியது டெல்ஹி , புகைப்படம் கடன் , ஸ்டாக் படங்கள் , மஞ்சள் பற்கள் , மஞ்சள் பற்கள் காரணங்கள் , மஞ்சள் பற்கள் வைத்தியம் ,