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Arena Pharmaceuticals presents late-breaking data on clinician and patient reported outcomes from..


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Etrasimod 2 mg treatment group achieved statistical significance in the percentage change in weekly peak pruritis (PP-NRS), in the change in Dermatology Life Quality Index (DLQI), and in the change in Patient-Oriented Eczema Measure (POEM)
Etrasimod 2 mg was generally well tolerated, consistent with data in previous trials
Park City, Utah, April 23, 2021 - Arena Pharmaceuticals, Inc. (Nasdaq: ARNA) today announced data at a late-breaking session at the American Academy of Dermatology VMX Experience. Etrasimod, a novel investigational drug candidate to treat moderate-to-severe atopic dermatitis (AD), demonstrated statistical significance in both clinician and patient reported outcomes in the ADVISE Phase 2b clinical trial. Etrasimod is a highly selective, once-daily, oral sphingosine 1-phosphate (S1P) receptor modulator. Today s results are presented by Emma Guttman-Yassky, MD, PhD, Waldman Professor and Chairwoman, The Kimberly and Eric J. Waldman Departm ....

United States , Park City , Patrick Malloy , Emma Guttman Yassky , Pauld Streck , Ericj Waldman Department Of Dermatology , Arena Pharmaceuticals Inc , Exchange Commission , American Academy Of Dermatology , Icahn School Of Medicine At Mount Sinai , Arena Pharmaceuticals , Clinical Development , Investor Relations Corporate Communications , Dermatology Life Quality Index , Patient Oriented Eczema Measure , American Academy , Waldman Professor , Icahn School , Senior Vice President , Chief Medical , Eczema Area , Severity Index , Investigator Global Assessment , Atopic Dermatitis , Looking Statements , Private Securities Litigation Reform Act ,

Kyowa Kirin Announces Positive Phase 2 Results for KHK4083 in Patients with Moderate to Severe Atopic Dermatitis


Press release content from Business Wire. The AP news staff was not involved in its creation.
Kyowa Kirin Announces Positive Phase 2 Results for KHK4083 in Patients with Moderate to Severe Atopic Dermatitis
February 18, 2021 GMT
TOKYO (BUSINESS WIRE) Feb 18, 2021
For Medical Media only. Kyowa Kirin Co., Ltd. (TSE: 4151, President and CEO: Masashi Miyamoto, “Kyowa Kirin”), a global specialty pharmaceutical company that strives to create new value through the pursuit of advances in life sciences and technologies, announces today that the Phase 2 study of investigational agent KHK4083 in patients with atopic dermatitis has met the primary endpoint.
KHK4083 is a potential first-in-class, anti-OX40 fully human monoclonal antibody for the treatment of autoimmune diseases, including atopic dermatitis. KHK4083 was first discovered by Kyowa Kirin, and is produced with the Company’s patented POTELLIGENT ® defucosylation technology to enhance its antibody dependen ....

United States , Masashi Miyamoto , Stacey Minton , Emma Guttman Yassky , Asia Pacific , Tomomasa Yagisawa , Lauren Walrath , Hiroki Nakamura , A Global Specialty Pharmaceutical Company , Kyowa Kirin Group , Icahn School Of Medicine At Mount Sinai , Kyowa Kirin Co Ltd , Department Of Dermatology , Kyowa Kirin International , Medical Media , Kyowa Kirin , Eczema Area , Severity Index , Global Assessment , System Chair , Waldman Professor , Icahn School , Mount Sinai , Inflammatory Skin Diseases , Yoshifumi Torii , Executive Officer ,