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Researchers map the impact of Covid-19 on the mental well-being of Israelis

During the six weeks between the end of the first COVID-19 outbreak in Israel and the beginning of the second one (late April to early June of 2020), researchers at the Weizmann Institute of Science initiated a study that encompassed more than 12,000 responses from nearly 5,000 respondents to digital questionnaires, in an attempt to assess and understand the mental toll of the pandemic on the country's adult population. ....

United States , Ron Rotkopf , Hagai Rossman , Smadar Shilo , Eran Segal , Emily Henderson , Yael Kuperman , Ayya Keshet , Orit Nuttman Shwartz , Asaf Benjamin , Maya Amitai , Max Planck Institute Of Psychiatry , Weizmann Institute Of Science , School Of Social Work At Sapir College , Mathematics Department , Weizmann Institute Neurobiology Department , Weizmann Institute , Life Sciences Core Facilities Department , Schneider Children Medical Center , Molecular Psychiatry , Alon Chen , Neurobiology Department , Max Planck Institute , Computer Science , Applied Mathematics Department , Noa Eren ,

Weizmann Institute Uncovers Secret of Hunger Switch in the Brain | The Jewish Press - JewishPress.com | Jewish Press News Desk | 4 Iyyar 5781 – April 16, 2021


Photo Credit: Image by Gerd Altmann from Pixabay
Being constantly hungry, no matter how much you eat – that’s the daily struggle of people with genetic defects in the brain’s appetite controls, and it often ends in severe obesity. In a study published in Science on April 15, researchers at the Weizmann Institute of Science, together with colleagues from the Queen Mary University of London and the Hebrew University of Jerusalem, have revealed the mechanism of action of the master switch for hunger in the brain: the melanocortin receptor 4, or MC4 receptor for short. They have also clarified how this switch is activated by setmelanotide (Imcivree), a drug recently approved for the treatment of severe obesity caused by certain genetic changes. These findings shed new light on the way hunger is regulated and may help develop improved anti-obesity medications. ....

Israel General , Moran Shalev Benami , Oksana Degtjarik , Vadivel Prabahar , Gerd Altmann , Yoav Peleg , Fabrizio Fierro , Nicolasj Roth , Vidicha Chunilal , Peterj Mccormick , Lif Chan , Danny Ben Zvi , Amandeep Kaur Gill , Joaquin Botta , Weizmann Institute Of Science , Tauro Career Development , Leadership Program , Wolf Lebovic Lab , Magnetic Resonance Research , Weizmann Life Sciences Core Facilities Department , Queen Mary University Of London , Hebrew University Of Jerusalem , Ilse Katz Institute For Material Sciences , Structural Biology Department , Biomedical Research , Photo Credit ,