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Scientists Identify Genetic Pathway that Suppresses Lou Gehrig's Disease


Date Time
Scientists Identify Genetic Pathway that Suppresses Lou Gehrig’s Disease
Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig’s Disease (ALS).
Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). In this study, the research team has identified a neuroprotective pathway of like-Sm protein 12 (LSM12) and exchange protein directly activated by cyclic AMP 1 (EPAC1) that sustains the nucleocytoplasmic RAN gradient and thereby suppresses NCT dysfunction by the C9ORF72-derived poly (glycine-arginine) protein. ....

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Arts and Culture Queen Mary launches its Conversations Week


Queen Mary University of London
In 2020, Arts and Culture at Queen Mary University of London invited UK-based artists to converse with academics from across the university, using its Higher Education Innovation Fund. A dentist spoke to a sculptor. A mathematician to a choreographer. A dramatist to an opera singer.
While an unforeseen pandemic limited human contact for many of us, these artists and academics found ways to talk. They held conversations about climate change, mental health, housework, racism, childcare, justice, wellbeing. They exchanged knowledge. Expertise. Then the artists set to work.
The results are original artworks and creative responses that could not have happened without conversations between academics and artists. They remind us of the power of art and the impact of connecting deep thinkers across fields. Watch the video on Vimeo. ....

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Shutting nano-gate


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Shutting nano-gate
Researchers at Osaka University create voltage-controlled nanopores that can trap particles as they try to pass through, which may lead to single-molecule sensors, along with cheaper and faster genomic sequencing
Scientists from the Institute of Scientific and Industrial Research at Osaka University fabricated nanopores in silicon dioxide, that were only 300 nm, in diameter surrounded by electrodes. These nanopores could prevent particles from entering just by applying a voltage, which may permit the development of sensors that can detect very small concentrations of target molecules, as well as next-generation DNA sequencing technology.
Nanopores are tiny holes that are wide enough for just a single molecule or particle to pass through. The motion of nanoparticles through these holes can usually be detected as an electrical signal, which makes them a promising platform for novel single-particle sensors. However, control of the motion o ....

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Scientists unearth meteorite


Scientists unearth meteorite
March 17, 2021
Scientists believe they have identified a meteorite formed in the first million years of our solar system, making it the oldest known meteor of volcanic origin.
The space rock, which began its journey some 4.5 billion years ago, has already proved an exceptional witness to the building blocks of the planets. Known as Erg Chech 002, the meteorite was discovered in May 2020 by meteor hunters in the Algerian Sahara desert. It had rested undisturbed for at least 100 years , according to Jean-Alix Barrat, a geochemist at France’s Brest University.
In a recent study published in the Proceedings of National Academy of Sciences journal, Barrat and his colleagues describe its discovery and several rare features. ....

Derg Chech , Jean Alix Barrat , France Brest University , Proceedings Of National Academy Sciences , Algerian Sahara , National Academy , பிரான்ஸ் ப்ரெஸ்ட் பல்கலைக்கழகம் , அல்ஜீரியன் சஹாரா , தேசிய கலைக்கழகம் ,

Grazing livestock could reduce greenhouse gases in atmosphere, study shows


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Grazing livestock could reduce greenhouse gases in atmosphere, study shows
An innovative approach to livestock grazing could help eliminate climate change-causing greenhouse gases, according to a new study by University of Alberta biologists. 
The research shows that a strategy called adaptive multi-paddock (AMP) grazing extracts methane gas from the atmosphere, locking it inside the soil through microbial activity. Methane gas has a climate warming effect that is 28 times more potent than carbon dioxide over a 100-year time frame. 
“Grasslands are the most endangered ecosystem type worldwide because of agricultural development and tillage,” said Mark Boyce, professor in the Department of Biological Sciences and supervising author on the project. ....

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