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New biological antibiotics can beat tuberculosis


New biological antibiotics can beat tuberculosis
This marks the first time that researchers have managed to develop a ‘biological antibiotic’ from human antibodies.
Dr. Natalia Freund in her lab. Photo courtesy of Tel Aviv University
Researchers at Tel Aviv University have demonstrated in laboratory mice that monoclonal antibodies can be substituted for antibiotics to hinder the growth of tuberculosis germs.
It’s estimated that around a quarter of the world’s population is infected by tuberculosis. In Israel, there are about 200 cases a year. Antibiotics are the usual course of treatment, but antibiotic-resistant strains of tuberculosis are now as high as 40 percent in some countries. ....

United States , Natalia Freund , Nature Communications , Researchers At Tel Aviv University , Tel Aviv University , Avia Watson , Sackler Medical Faculty , Tel Aviv , Monoclonal Antibodies , ஒன்றுபட்டது மாநிலங்களில் , நடாலியா ஃப்ரீண்ட் , இயற்கை தகவல்தொடர்புகள் , ஆராய்ச்சியாளர்கள் இல் தொலைபேசி அவிவ் பல்கலைக்கழகம் , தொலைபேசி அவிவ் பல்கலைக்கழகம் , அவிய வாட்சன் , ஸ்யாக்லர் மருத்துவ ஆசிரிய , தொலைபேசி அவிவ் ,

Human monoclonal antibodies can act as a substitute for traditional antibiotics


Human monoclonal antibodies can act as a substitute for traditional antibiotics
In the course of a new and groundbreaking study, led by Dr, Natalia Freund and the doctoral candidate Avia Waston at the Sackler Medical Faculty, the research group succeeded in isolating monoclonal antibodies, which hindered the growth of tuberculosis germs in laboratory mice. The antibodies were isolated from a patient who had succumbed to active tuberculosis disease but had since recovered.
This is, in fact, the first time in history that researchers have managed to develop a biological antibiotic and demonstrate that human monoclonal antibodies can act as a substitute for the traditional chemical antibiotics and protect mice from pathogenic bacterial challenge. The study was carried out in a collaboration with two additional laboratories from the US and China and was published in the prestigious scientific journal ....

Avia Waston , Natalia Freund , Emily Henderson , Nature Communications , Sackler Medical Faculty , Cell Wall , நடாலியா ஃப்ரீண்ட் , எமிலி ஹென்டர்சன் , இயற்கை தகவல்தொடர்புகள் , ஸ்யாக்லர் மருத்துவ ஆசிரிய , செல் சுவர் ,

Biological therapy has proved a suitable alternative to antibiotics

Tel Aviv University researchers have developed a biological substitute for the treatment of tuberculosis, which in the future could serve as an alternative for the traditional chemical antibiotic therapy.
Dr. Freund: Advances in molecular medicine enable us to develop new tools to rout microbes, which can also solve the problem of drug-resistant germs .
This groundbreaking study has been published in the prestigious scientific journal Nature Communications. ....

Avia Waston , Natalia Freund , Nature Communications , Sackler Medical Faculty , Cell Biology , Molecular Biology , Medicine Health , Infectious Emerging Diseases , Internal Medicine , நடாலியா ஃப்ரீண்ட் , இயற்கை தகவல்தொடர்புகள் , ஸ்யாக்லர் மருத்துவ ஆசிரிய , செல் உயிரியல் , மூலக்கூறு உயிரியல் , மருந்து ஆரோக்கியம் , தடுப்பு மருந்துகள் , தொற்று வளர்ந்து வருகிறது நோய்கள் , உள் மருந்து ,