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IMAGE: Gang Fang, PhD, Associate Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai
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Credit: Mount Sinai Health System
Journal Name:
Nature Methods
Title of the Article: Discovering multiple types of DNA methylation from individual bacteria and microbiome using nanopore sequencing
Corresponding Author: Gang Fang, PhD
Bottom Line:
Bacterial DNA methylation occurs at diverse sequence contexts and plays important functional roles in cellular defense and gene regulation. An increasing number of studies have reported that bacterial DNA methylation has important roles affecting clinically relevant phenotypes such as virulence, host colonization, sporulation, biofilm formation, among others.