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1,500-Year-Old DNA Reveals Face of Chinese Emperor Wu

1,500-Year-Old DNA Reveals Face of Chinese Emperor Wu
greekreporter.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from greekreporter.com Daily Mail and Mail on Sunday newspapers.

Shanghai , China , Mongolia , Xianbei , Shaanxi , Gang-fang , Yunnan , Turkey , Turks , Chinese , Pianpian-wei , Emperor-wu

Genomic Tweezer Revolutionizes Precision in Microbiome Research

Genomic Tweezer Revolutionizes Precision in Microbiome Research
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Health-care , Icahn-school-of-medicine-at-mount-sinai , National-institutes-of-health , Genomic-sciences , Nature-methods , Icahn-school , Mount-sinai , Microbial-world , Gang-fang , National-institutes ,

Genomic 'tweezer' ushers in a new era of precision in microbiome research

Genomic 'tweezer' ushers in a new era of precision in microbiome research
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

Genomic-sciences , Icahn-school-of-medicine-at-mount-sinai , Icahn-school , Mount-sinai , Nature-methods , Gang-fang ,

Are Scientists Being Fooled by Bacteria?

For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off

China , Gang-fang , Yunnan , Chinese , National-natural-science-foundation-of-china , National-institutes-of-health , Irmat-hirschl-monique-weill-caulier , Department-of-scientific-computing , Nash-family-foundation , Chinese-academy-of-sciences , Genomic-sciences-at-icahn-mount-sinai

New study finds if bacteria confound genetic switch

For decades, a small group of medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off

Icahn-school-of-medicine , Genomic-sciences-at-icahn-mount-sinai , Icahn-school , Gang-fang , Associate-professor , Genomic-sciences , Icahn-mount , New , Tudy , Inds , F

Science News | New Study Finds if Bacteria Confound Genetic Switch

Get latest articles and stories on Science at LatestLY. For decades, a small group of medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumours. According to a new study by researchers at the Icahn School of Medicine, there may be a hitch: much of the evidence of presence of the DNA tagging system, in higher organisms may be due to bacterial contamination, which was difficult to spot using current experimental methods. Science News | New Study Finds if Bacteria Confound Genetic Switch.

New-york , United-states , Icahn-school-of-medicine , Genomic-sciences-at-icahn-mount-sinai , Icahn-school , Gang-fang , Associate-professor , Genomic-sciences , Icahn-mount ,

Discovering DNA methylation from bacteria and microbiome using nanopore technology

Discovering DNA methylation from bacteria and microbiome using nanopore technology
Journal name:
Nature Methods
Title of the article: Discovering multiple types of DNA methylation from individual bacteria and microbiome using nanopore sequencing
Corresponding author: Gang Fang, PhD
Bottom line:
Bacterial DNA methylation occurs at diverse sequence contexts and plays important functional roles in cellular defense and gene regulation. An increasing number of studies have reported that bacterial DNA methylation has important roles affecting clinically relevant phenotypes such as virulence, host colonization, sporulation, biofilm formation, among others.
Bacterial methylomes contain three primary forms of DNA methylation: N6-methyladenine (6 mA), N4-methylcytosine (4mC) and 5-methylcytosine (5mC). The widely used bisulfite sequencing for DNA methylation mapping in mammalian genomes are not effective at resolving bacterial methylomes. Single molecule real-time (SMRT) can effectively map 6mA and 4mC events, and have empowered the study of >4,000 bacterial methylomes in the past ten years. However, SMRT sequencing cannot effectively detect 5mC methylation.

Emily-henderson , Gang-fang , Mount-sinai , Bacteria , Dna , Dna-methylation , Gene , Genes , Genetic , Genetics , Genomic

DNA methylation from bacteria & mircobiome using nanopore technology discovered

E-Mail
IMAGE: Gang Fang, PhD, Associate Professor, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai
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Credit: Mount Sinai Health System
Journal Name:
Nature Methods
Title of the Article: Discovering multiple types of DNA methylation from individual bacteria and microbiome using nanopore sequencing
Corresponding Author: Gang Fang, PhD
Bottom Line:
Bacterial DNA methylation occurs at diverse sequence contexts and plays important functional roles in cellular defense and gene regulation. An increasing number of studies have reported that bacterial DNA methylation has important roles affecting clinically relevant phenotypes such as virulence, host colonization, sporulation, biofilm formation, among others.

Elizabeth-dowling , Why-the-research-is-interesting , Public-affairs , Journal-name , Gang-fang , Research-is-interesting , Mount-sinai , Biology , Bacteriology , Biotechnology , Cell-biology , Genetics

China Marks the Wuhan Lockdown Anniversary Amid Spiraling COVID-19 Cases and With Risky Holiday Travel Looming

China Marks the Wuhan Lockdown Anniversary Amid Spiraling COVID-19 Cases and With Risky Holiday Travel Looming
Time
1/22/2021
Charlie Campbell / Changsha and Wuhan
© HECTOR RETAMAL/AFP via Getty Images
A woman walks along a street near a market in Wuhan, China's central Hubei province on January 19, 2021.
When authorities came to Dr. Liu Chun’s hospital in the central Chinese city of Changsha with a request for 130 volunteers, it took just two hours for all slots to be filled. As a respiratory doctor specializing in ICU patients, Liu felt it was her duty to join the group of medical workers summoned 340 kilometers north, to Wuhan, where rumors of a mysterious pneumonia-like illness had been circulating for weeks. At first, Liu, 48, wasn’t terribly worried. Her husband and 12-year-old daughter were supportive; she didn’t bother telling her elderly parents of her plans.

Changsha , Hunan , China , Yangtze-river , China-general , Tongji , Sichuan , Shanghai , Gang-fang , Yunnan , Huangzhuang , Guangdong