Methotrexate alleviates pain among patients with hand osteoarthritis and concurrent synovitis

1. Methotrexate 20 mg once weekly resulted in significant pain reduction among patients with hand osteoarthritis of the inflammatory phenotype. 2. Adverse events in the treatment group were comparable to the placebo group. Evidence Rating Level: 1 (Excellent) Study Rundown: Hand osteoarthritis is a debilitating condition with limited treatment options. Topical therapy, oral analgesics, and

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Australia , ,Rating Level ,Active Rheumatoid Arthritis ,Between Nov ,Hand Osteoarthritis ,Methotrexate ,Musculoskeletal Pain ,Osteoarthritis ,Rheumatology ,Synovitis ,Chronic Disease ,