Both teams put up a strong display in the opening minutes of the encounter, nevertheless, it was the hosts who took the initiative after 20 minutes through Giacomo Bonaventura.
Profiting from a poor clearance by Arkadiusz Reca, the Italian midfielder picked up the ball and fired a right-footed shot from the edge of the box past goalkeeper Alex Cordaz.
In the 32nd minute, the hosts doubled their advantage through Dusan Vlahovic, who scored from close range after collecting a pass from Frenchman Franck Ribery.
Crotone stepped up their game in the second-half but it was Prandelli’s men who kept creating goalscoring chances. Gaetano Castrovilli assisted Vlahovic twice, but the Serbian failed to bury the ball inside the net.