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IMAGE: Above are fluorescent images of genetically identical yeast cells, marked for some of the biomarkers that UT Southwestern researchers discovered help to predict cell fate. The yellow is the nucleus,...
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Credit: UT Southwestern Medical Center
DALLAS - Jan. 11, 2021 - A set of biomarkers not traditionally associated with cell fate can accurately predict how genetically identical cells behave differently under stress, according to a UT Southwestern study. The findings, published by
Cell Reports as a Dec. 1 cover story, could eventually lead to more predictable responses to pharmaceutical treatments.
Groups of the same types of cells exposed to the same stimuli often display different responses. Some of these responses have been linked to slight differences in genetics between individual cells. However, even genetically identical cells can diverge in behavior.