Scientists at top Lancashire university make headway in developing Covid-19 vaccine nasal spray
Researchers at a top Lancashire university have successfully engineered a Covid-19 vaccine which can be administered through the nose.
The researchers, from Lancaster University, administered two doses of the vaccine via a nasal spray in animal trials, which are the first stage in vaccine development.
These doses elicited robust antibodies and T-cell responses which were enough to be able to neutralize SARS-CoV-2.
Thy also found there was a significant reduction in lung pathology, inflammation and clinical disease in the rodents who received the vaccine.
The vaccine is based on a common poultry virus called the Newcastle Disease Virus (NDV), which can replicate in humans - but is harmless.